ID A0A287BQA2_PIG Unreviewed; 329 AA.
AC A0A287BQA2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 {ECO:0000313|EMBL:HDA81033.1};
DE SubName: Full=Potassium channel tetramerization domain containing 13 {ECO:0000313|Ensembl:ENSSSCP00000058355.1};
GN Name=KCTD13 {ECO:0000313|Ensembl:ENSSSCP00000058355.1,
GN ECO:0000313|VGNC:VGNC:89393};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000058355.1, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000058355.1, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000058355.1,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:HDA81033.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30723633; DOI=.7717/peerj.6374;
RA Gilbert D.G.;
RT "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL PeerJ 7:E6374-E6374(2019).
RN [3] {ECO:0000313|Ensembl:ENSSSCP00000058355.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BACURD family.
CC {ECO:0000256|ARBA:ARBA00025759}.
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DR EMBL; DQIR01125557; HDA81033.1; -; Transcribed_RNA.
DR EMBL; DQIR01165992; HDB21469.1; -; Transcribed_RNA.
DR STRING; 9823.ENSSSCP00000058355; -.
DR PaxDb; 9823-ENSSSCP00000023850; -.
DR Ensembl; ENSSSCT00000043623.2; ENSSSCP00000058355.1; ENSSSCG00000040888.3.
DR VGNC; VGNC:89393; KCTD13.
DR eggNOG; KOG2716; Eukaryota.
DR GeneTree; ENSGT00950000183143; -.
DR OMA; PPLENCA; -.
DR OrthoDB; 2912088at2759; -.
DR Reactome; R-SSC-9696264; RND3 GTPase cycle.
DR Reactome; R-SSC-9696270; RND2 GTPase cycle.
DR Proteomes; UP000008227; Chromosome 3.
DR Bgee; ENSSSCG00000040888; Expressed in prefrontal cortex and 42 other cell types or tissues.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0031267; F:small GTPase binding; IEA:Ensembl.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:Ensembl.
DR GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR GO; GO:0035024; P:negative regulation of Rho protein signal transduction; IBA:GO_Central.
DR GO; GO:0050806; P:positive regulation of synaptic transmission; IEA:Ensembl.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0043149; P:stress fiber assembly; IEA:Ensembl.
DR CDD; cd18400; BTB_POZ_KCTD13_BACURD1; 1.
DR InterPro; IPR045068; BACURD1-3.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR PANTHER; PTHR11145; BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER; 1.
DR PANTHER; PTHR11145:SF18; BTB_POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 1; 1.
DR Pfam; PF02214; BTB_2; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 41..109
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 36405 MW; 576D9770E0A9CCB1 CRC64;
MSAEASGPAA AEAQSLEVPK PAGLEPGSAA YGLKPLTPNS KYVKLNVGGS LHYTTLRTLT
GQDTMLKAMF SGRAEVLTDA GGWVLIDRSG RHFGTILNYL RDGSVPLPES TRELGELLGE
ARYYLVQGLI EDCQLALQQK RENVSPLCLI PTVTSPREEQ QLLASTSKPV VKLLHNRSNN
KYSYTSTSDD NLLKNIELFD KLALRFHGRL LFLKDVLGDE ICCWSFYGQG RKIAEVCCTS
IVYATEKKQT KVEFPEARIF EETLNILIYE TPRGPDPALL EATGGAAGGG GASRGEDEEN
REHRVRRIHV RRHITHDERP HGQQIVFKD
//
