ID   A0A287CU42_ICTTR        Unreviewed;      1026 AA.
AC   A0A287CU42;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=GTF2I repeat domain containing 1 {ECO:0000313|Ensembl:ENSSTOP00000024794.1};
GN   Name=GTF2IRD1 {ECO:0000313|Ensembl:ENSSTOP00000024794.1};
OS   Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS   tridecemlineatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC   Xerinae; Marmotini; Ictidomys.
OX   NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000024794.1, ECO:0000313|Proteomes:UP000005215};
RN   [1] {ECO:0000313|Proteomes:UP000005215}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Assembly & Analysis Group;
RG   Computational R&D Group;
RG   and Sequencing Platform;
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT   "The Draft Genome of Spermophilus tridecemlineatus.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSTOP00000024794.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; AGTP01053389; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A287CU42; -.
DR   STRING; 43179.ENSSTOP00000024794; -.
DR   Ensembl; ENSSTOT00000033871.1; ENSSTOP00000024794.1; ENSSTOG00000014343.3.
DR   GeneTree; ENSGT00940000159414; -.
DR   InParanoid; A0A287CU42; -.
DR   Proteomes; UP000005215; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR   GO; GO:0014886; P:transition between slow and fast fiber; IEA:Ensembl.
DR   Gene3D; 3.90.1460.10; GTF2I-like; 5.
DR   InterPro; IPR004212; GTF2I.
DR   InterPro; IPR036647; GTF2I-like_rpt_sf.
DR   InterPro; IPR016659; TF_II-I.
DR   PANTHER; PTHR46304; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR46304:SF1; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF02946; GTF2I; 5.
DR   PIRSF; PIRSF016441; TF_II-I; 1.
DR   SUPFAM; SSF117773; GTF2I-like repeat; 5.
DR   PROSITE; PS51139; GTF2I; 5.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REGION          98..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          438..489
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          942..980
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        959..980
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1026 AA;  112507 MW;  D432469D7764C047 CRC64;
     MALLGKRCDL PANGCGPDRW SSAFARKDEI ITSLVSALDS MCSALSKLNA EVACVAVHDE
     SAFVVGTEKG RVFLSARKEL QADFLRFCRG PLWKDPEGEH PKKVQRGEGG CRGTPRSSLE
     RGSDVYLLRK MVEEVFDVLY SEALGRASVV PLPYERLLRE PGLLAVQGLP EGLAFRRPAE
     YDPEALMAIL EHSHRIRFKL KRPLEDGGRD SKALVELNGI SLLPRGSRDC SLHGQVPKAA
     PQDLPPTATS SSVASFLYTT ALPVHTLREL KQEPPSCPLA PGDLGLGRPG PEPKAPGAQD
     FSDCCGNTPP GPGGPLIQNV HASKRILFSI VHDKSEKWDA FIRETEDINT LRECVQILFN
     SRYAEALGLD HMVPVPYRKI ACDPEAVEIV GIPDKIPFKR PCTYGVPKLK RILEERHSIH
     FIIKRMFDER IFTGNKFTKD PTKLEPASPP EDTSAEVPRA TMLDLAATAR SDKGSVSEDC
     GPGTSGELGI LRPIKIEPED LDIIQVTVPD PSPTSEEMTD SMPGHLPSED SGYGMEMLTG
     KRMAHEVPLH PADSPGDVIR PLRKQVELLF NSRYAKAIGI SEPVKVPYSK FLMHPEELFV
     VGLPEGISLR RPNCFGIAKL RKILEASNSI QFVIKRPELL TEGVKEPVVD SQERDPGDPL
     VDESLKRQGF QENFDARLSR IDIANTLREQ VQDLFNKKYG EALGIKYPVQ VPYKRIKSNP
     GSVIIEGLPP GIPFRKPCTF GSQNLERILA VADKIKFTVT RPFQGLIPKP GKRPRRVGTL
     KALSSSADED DANRLGEKVI LREQVKELFN EKYGQCPLRP HGSAGQPWDP PTAHPDRAAL
     IGPADLLTVT PSWGVTRDHC PPHPPGEALG LNRPVLVPYK LIRDSPDAVE VTGLPDDIPF
     RNPNTYDIHR LEKILKAREH VRMVIINQLQ PFAELCNDAK VPAKDSNVPK RKRKRVSEGN
     SVSSSSSSSS SSSSNPESVA PTNQISLVVK LHRPGLRQAS LWPLPLARAG LPAPGGGVGA
     RGGSGL
//