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Database: UniProt
Entry: A0A287CUL8_ICTTR
LinkDB: A0A287CUL8_ICTTR
Original site: A0A287CUL8_ICTTR 
ID   A0A287CUL8_ICTTR        Unreviewed;      2997 AA.
AC   A0A287CUL8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   12-AUG-2020, entry version 15.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSTOP00000024971};
GN   Name=CENPF {ECO:0000313|Ensembl:ENSSTOP00000024971};
OS   Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS   tridecemlineatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC   Xerinae; Marmotini; Ictidomys.
OX   NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000024971, ECO:0000313|Proteomes:UP000005215};
RN   [1] {ECO:0000313|Ensembl:ENSSTOP00000024971, ECO:0000313|Proteomes:UP000005215}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Assembly & Analysis Group;
RG   Computational R&D Group;
RG   and Sequencing Platform;
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT   "The Draft Genome of Spermophilus tridecemlineatus.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSTOP00000024971}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2017) to UniProtKB.
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DR   EMBL; AGTP01080349; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGTP01080350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGTP01080351; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005335030.1; XM_005334973.2.
DR   Ensembl; ENSSTOT00000032047; ENSSTOP00000024971; ENSSTOG00000034538.
DR   GeneID; 101971932; -.
DR   CTD; 1063; -.
DR   GeneTree; ENSGT00730000111187; -.
DR   OrthoDB; 205405at2759; -.
DR   Proteomes; UP000005215; Unassembled WGS sequence.
DR   GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR   GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR   GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR   GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR   GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR   GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 3.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT   DOMAIN          1..302
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1890..2032
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2128..2267
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2310..2449
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2852..2896
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          206..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          247..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          466..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2775..2997
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..138
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          159..186
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          275..337
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          500..645
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          653..715
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          741..768
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          834..868
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          894..942
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          964..994
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1024..1051
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1059..1097
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1113..1162
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1205..1239
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1281..1322
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1334..1354
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1434..1454
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1543..1606
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1620..1640
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1764..1812
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1820..1847
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1922..1994
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2013..2047
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2055..2082
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2111..2131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2139..2194
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2202..2286
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2318..2492
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2500..2541
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2559..2607
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2615..2746
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2754..2774
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        2792..2815
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2838..2852
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2907..2961
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2997 AA;  345020 MW;  5E0C0FA54934CA15 CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDTLEAALQK QKQKVENEKN
     EGTNLKRENQ RLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLSAGKKQ IEKLEQELKR
     YKSELERSQQ AAQSADVSLN LCNTPQKLFA TPLTPSSKYE DLKEKYNKEV EERKRLEAEV
     KALQSKKASQ AVPQTLMNHR DIARHQTSSS VFSWQEEKTP NRLSSNSQKT PNRRDFFASH
     IFGEEEVTPS RSTFQTGKRD FSSSGCDNSS NSHLLDQCKA QNQELRSKVN ELELRLQAQE
     KEMKGQVNKF LEVQLQLEKT KIELTEKEKV LNRNKDELVR TTAQYDQAAT KCTALEKKLK
     KLTEDLSCQR QNAESARCSL EQKIKEKEKE LQEELSRQHR SFQTLDQECT QMKARLTQEL
     QQAKNTLNIL QAELDKVTSV KQQLEKNLEE FKQRVSKMEQ AIQASQIKED ELRRSSEEMK
     KENGLLKSQS EQRAREVCHL EEELRKVKES LNQSQNFAEE MRAKNTSQET MLRDLQDKIN
     QQENSLTLEK LKLALADLEK QRDCSQDLLK KREHHIEQLN DKLSKIEKES KALLSALELK
     KKEYEELKEE KTQFSHWKNE NEKLLNQLES EKESLQSKIN HLETCLKTQQ IKSHEYNERE
     KTLEMERENL NVEIRNLHNV IESKTMEIET QKKAYVELQQ KAENSDQKHK KEIENMCLKT
     SELTGQVGDL EHKLQLLSSE IMDKDQHYQN LHAEYENLRE LLRSKDSNLV SNENHHRSCL
     VFEQQPTVNN SFANLTGEQG TMLSEISKCH LGADQSPKHS ALLQNRVVSL EFSLESQKQM
     NSDLQKQCEE LVQVKGEIEE NLMKAEQMHQ SFVAETSHRI SKLQEDTVVH QNVVNETLVA
     LENKEKELQL LKEQLEAEQA EIQELKKSNH LLEVSLKELQ LLSETLSSEK KEMSSIISLS
     KKEIEELTQD NGALKEINET LSQEKMNLIQ KNENFSSCIE EREKSISELS DQYKQERLLL
     QQRCEETGSA LEDLHEKYKA VQEKNSELEC LLKECTGICE NRKTELEQLK EAFAKEHQEF
     LTKLAFAEER NQKLMLELGI VQQTLRSEII DIQNNSQNEA NGLKQEIMTL KEEQNKLQKE
     VNDLLQENEQ LMKLTKTELE QQHPDLETIR DSVKETENEI SKCDFQHHMD LKVKDIAPGS
     CTTQFIQLEA LVKNMELKLQ QSEKEKECLQ QELQTIRGKL GTGNLQDDQP QEISGLKDYE
     IDTEERYLSV LHELSTSQND NAQLHCSLQT AVNKLNELEK MCEALRAEKL ELVSELNDSR
     SECITTTSKM AEEVEKLVSE VKILNDENGL LQDELVKEMS DGEYGEQQNE QMSASLNPLD
     DSNSYERLTL SNKEVQMHFA ELHEKFSSLQ SEHKILHDQH CQMSSKMAEL RSYVDTLKAE
     NSALSVNLRN LQGELVKDLK PEPEEGRNLS LSFSCVTDSP SLTSFGESSF YKDVLEQTGD
     LSLLSSLEGS ISANLSNIDE VSCSRLEENL AKKEIPTAPM KSVEELETLC QVYLESLKNL
     EEKIESEGIL KNKEIQELEQ LLSSERKELD CLRKQYLSEN EQWQQKLTSV TLEMESKLAA
     EKKQTEHLSL ELEVARLQLQ GLDLSSRSLL DSEVEAIRDQ NDSCDIKEEH NSETTEETLK
     QDIHQICDKD VQQDLNLEIE KISETNTNTA RLIGEESGEK SSKTNYEIPA EDKIQGYSGC
     ISELAFSGPN TLVPMDFLEN QAYIQNLQLQ VKETSNENSR LLHAIEDRDK KVESLLHEIK
     ELDSKLNLQE AQLKTKIESC MQWEKIVEEL KKEKSDLSEK LESFSHNQDN QESCQRVEAS
     NGFSSDLEMG TDESLHEVIE GNISLADDKW KEKFLDVENE LNRLTFEKAR IEHHALSVEA
     DLEIVQTEKV RLEKDRENKQ KVIVCLEEEL SVVTSEKNRL QGELDSVSKE NEALDQMSAK
     MKEKIQELES QHGESLHHIQ VVEAEVKDKT ELLQTLSSDV SELLKDKAHL QEQLQNLEED
     SQALSLAKCE LENQIGQLNQ EKGSLMRESE SLQAKLQESE HEKLAVSKAL EVALMEKGEF
     AERLGSTQEE VHQLRRGIEK LRVRIEADEK KQLHVMEKLR ESQRENDSLK DKVENLEREL
     QMSEENQELV ILDAENFKAE METQKTQMEE MAESLNVFKS DLVTVRAEKE NLTKQLQEKQ
     GQVSELNELL SSLKNLLEEK EQEKIRMKEE SRIEVEMLQT QLKELNEEVE ALYNDQETQK
     AKEQNSDPRG EEVCQLRSSF EKLKVHIEAD RKNQLQVLEQ LKESKHHADL LKERAENLER
     ELELSEKTQE HVILEANNSK AEVETLKAEI GEMTRNLRDL ELDLVHTRSE KENLTKELQK
     EQMRVSELEI QNSSFENLLQ EKEQEKIQMK EESEIAVEML QSQLKELNEK MTTLCNDQEA
     CKTKEQNLSN QVDSLELEKA QLLQSLDEAK TNYILLQSSV NSLIQEVEDG KQKLEKKDEE
     VSRLKHQIQD QEQLASKLSQ VEGEKQLWQK QKAELGNVTV ELEQKVQMLQ SRNDTLQDTF
     QALQHSYKDL ESELELTKRE KMSFVEKVNT MTAKETELQR EMHEMAQKTT ELKKEFSEEK
     SRLTEELKVM LEELNNSKMD HLKYVNQLKK ENERAQGKIK LLLKSCKQLE EEKKTLQKQL
     SQLEAAQKQK TGNVVEAKVD ELMTELKELK ETLEEKTKEA DEYLDKYCSL LISHENLEKA
     KEMLETQVAS LSLQQSKRDL RSSPLLTSPV PGPSPASSVR EKKSSSGQNK ASGKRERSSG
     IWENGGGLTP STPEMFPKKI RKTSKSGVQP AEDEEETEYE PEGLPEVVKK GFADIPTGKI
     SPYVLRRTTM ATRTSPRLAA QKLALSPLTS GKENLAESSK PTAGGSRSQK VKVAQQSQGG
     SGSAFQESTT KSLSVNHLPE RSSAVNPREG LRATRGRPAP SPGAAPEPRS SENCKVQ
//
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