ID A0A287CUL8_ICTTR Unreviewed; 2997 AA.
AC A0A287CUL8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 12-AUG-2020, entry version 15.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSTOP00000024971};
GN Name=CENPF {ECO:0000313|Ensembl:ENSSTOP00000024971};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000024971, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Ensembl:ENSSTOP00000024971, ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000024971}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (OCT-2017) to UniProtKB.
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DR EMBL; AGTP01080349; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01080350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01080351; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005335030.1; XM_005334973.2.
DR Ensembl; ENSSTOT00000032047; ENSSTOP00000024971; ENSSTOG00000034538.
DR GeneID; 101971932; -.
DR CTD; 1063; -.
DR GeneTree; ENSGT00730000111187; -.
DR OrthoDB; 205405at2759; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR GO; GO:0030496; C:midbody; IEA:Ensembl.
DR GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 3.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 1..302
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1890..2032
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2128..2267
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2310..2449
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2852..2896
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 206..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2775..2997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..138
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 159..186
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 275..337
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 500..645
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 653..715
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 741..768
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 834..868
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 894..942
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 964..994
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1024..1051
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1059..1097
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1113..1162
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1205..1239
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1281..1322
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1334..1354
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1434..1454
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1543..1606
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1620..1640
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1764..1812
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1820..1847
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1922..1994
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2013..2047
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2055..2082
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2111..2131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2139..2194
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2202..2286
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2318..2492
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2500..2541
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2559..2607
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2615..2746
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2754..2774
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2792..2815
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2838..2852
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2907..2961
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2997 AA; 345020 MW; 5E0C0FA54934CA15 CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDTLEAALQK QKQKVENEKN
EGTNLKRENQ RLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLSAGKKQ IEKLEQELKR
YKSELERSQQ AAQSADVSLN LCNTPQKLFA TPLTPSSKYE DLKEKYNKEV EERKRLEAEV
KALQSKKASQ AVPQTLMNHR DIARHQTSSS VFSWQEEKTP NRLSSNSQKT PNRRDFFASH
IFGEEEVTPS RSTFQTGKRD FSSSGCDNSS NSHLLDQCKA QNQELRSKVN ELELRLQAQE
KEMKGQVNKF LEVQLQLEKT KIELTEKEKV LNRNKDELVR TTAQYDQAAT KCTALEKKLK
KLTEDLSCQR QNAESARCSL EQKIKEKEKE LQEELSRQHR SFQTLDQECT QMKARLTQEL
QQAKNTLNIL QAELDKVTSV KQQLEKNLEE FKQRVSKMEQ AIQASQIKED ELRRSSEEMK
KENGLLKSQS EQRAREVCHL EEELRKVKES LNQSQNFAEE MRAKNTSQET MLRDLQDKIN
QQENSLTLEK LKLALADLEK QRDCSQDLLK KREHHIEQLN DKLSKIEKES KALLSALELK
KKEYEELKEE KTQFSHWKNE NEKLLNQLES EKESLQSKIN HLETCLKTQQ IKSHEYNERE
KTLEMERENL NVEIRNLHNV IESKTMEIET QKKAYVELQQ KAENSDQKHK KEIENMCLKT
SELTGQVGDL EHKLQLLSSE IMDKDQHYQN LHAEYENLRE LLRSKDSNLV SNENHHRSCL
VFEQQPTVNN SFANLTGEQG TMLSEISKCH LGADQSPKHS ALLQNRVVSL EFSLESQKQM
NSDLQKQCEE LVQVKGEIEE NLMKAEQMHQ SFVAETSHRI SKLQEDTVVH QNVVNETLVA
LENKEKELQL LKEQLEAEQA EIQELKKSNH LLEVSLKELQ LLSETLSSEK KEMSSIISLS
KKEIEELTQD NGALKEINET LSQEKMNLIQ KNENFSSCIE EREKSISELS DQYKQERLLL
QQRCEETGSA LEDLHEKYKA VQEKNSELEC LLKECTGICE NRKTELEQLK EAFAKEHQEF
LTKLAFAEER NQKLMLELGI VQQTLRSEII DIQNNSQNEA NGLKQEIMTL KEEQNKLQKE
VNDLLQENEQ LMKLTKTELE QQHPDLETIR DSVKETENEI SKCDFQHHMD LKVKDIAPGS
CTTQFIQLEA LVKNMELKLQ QSEKEKECLQ QELQTIRGKL GTGNLQDDQP QEISGLKDYE
IDTEERYLSV LHELSTSQND NAQLHCSLQT AVNKLNELEK MCEALRAEKL ELVSELNDSR
SECITTTSKM AEEVEKLVSE VKILNDENGL LQDELVKEMS DGEYGEQQNE QMSASLNPLD
DSNSYERLTL SNKEVQMHFA ELHEKFSSLQ SEHKILHDQH CQMSSKMAEL RSYVDTLKAE
NSALSVNLRN LQGELVKDLK PEPEEGRNLS LSFSCVTDSP SLTSFGESSF YKDVLEQTGD
LSLLSSLEGS ISANLSNIDE VSCSRLEENL AKKEIPTAPM KSVEELETLC QVYLESLKNL
EEKIESEGIL KNKEIQELEQ LLSSERKELD CLRKQYLSEN EQWQQKLTSV TLEMESKLAA
EKKQTEHLSL ELEVARLQLQ GLDLSSRSLL DSEVEAIRDQ NDSCDIKEEH NSETTEETLK
QDIHQICDKD VQQDLNLEIE KISETNTNTA RLIGEESGEK SSKTNYEIPA EDKIQGYSGC
ISELAFSGPN TLVPMDFLEN QAYIQNLQLQ VKETSNENSR LLHAIEDRDK KVESLLHEIK
ELDSKLNLQE AQLKTKIESC MQWEKIVEEL KKEKSDLSEK LESFSHNQDN QESCQRVEAS
NGFSSDLEMG TDESLHEVIE GNISLADDKW KEKFLDVENE LNRLTFEKAR IEHHALSVEA
DLEIVQTEKV RLEKDRENKQ KVIVCLEEEL SVVTSEKNRL QGELDSVSKE NEALDQMSAK
MKEKIQELES QHGESLHHIQ VVEAEVKDKT ELLQTLSSDV SELLKDKAHL QEQLQNLEED
SQALSLAKCE LENQIGQLNQ EKGSLMRESE SLQAKLQESE HEKLAVSKAL EVALMEKGEF
AERLGSTQEE VHQLRRGIEK LRVRIEADEK KQLHVMEKLR ESQRENDSLK DKVENLEREL
QMSEENQELV ILDAENFKAE METQKTQMEE MAESLNVFKS DLVTVRAEKE NLTKQLQEKQ
GQVSELNELL SSLKNLLEEK EQEKIRMKEE SRIEVEMLQT QLKELNEEVE ALYNDQETQK
AKEQNSDPRG EEVCQLRSSF EKLKVHIEAD RKNQLQVLEQ LKESKHHADL LKERAENLER
ELELSEKTQE HVILEANNSK AEVETLKAEI GEMTRNLRDL ELDLVHTRSE KENLTKELQK
EQMRVSELEI QNSSFENLLQ EKEQEKIQMK EESEIAVEML QSQLKELNEK MTTLCNDQEA
CKTKEQNLSN QVDSLELEKA QLLQSLDEAK TNYILLQSSV NSLIQEVEDG KQKLEKKDEE
VSRLKHQIQD QEQLASKLSQ VEGEKQLWQK QKAELGNVTV ELEQKVQMLQ SRNDTLQDTF
QALQHSYKDL ESELELTKRE KMSFVEKVNT MTAKETELQR EMHEMAQKTT ELKKEFSEEK
SRLTEELKVM LEELNNSKMD HLKYVNQLKK ENERAQGKIK LLLKSCKQLE EEKKTLQKQL
SQLEAAQKQK TGNVVEAKVD ELMTELKELK ETLEEKTKEA DEYLDKYCSL LISHENLEKA
KEMLETQVAS LSLQQSKRDL RSSPLLTSPV PGPSPASSVR EKKSSSGQNK ASGKRERSSG
IWENGGGLTP STPEMFPKKI RKTSKSGVQP AEDEEETEYE PEGLPEVVKK GFADIPTGKI
SPYVLRRTTM ATRTSPRLAA QKLALSPLTS GKENLAESSK PTAGGSRSQK VKVAQQSQGG
SGSAFQESTT KSLSVNHLPE RSSAVNPREG LRATRGRPAP SPGAAPEPRS SENCKVQ
//
