ID A0A287CYS6_ICTTR Unreviewed; 871 AA.
AC A0A287CYS6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=MORC family CW-type zinc finger 1 {ECO:0000313|Ensembl:ENSSTOP00000026409.1};
GN Name=MORC1 {ECO:0000313|Ensembl:ENSSTOP00000026409.1};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000026409.1, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000026409.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01085052; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01085053; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01085054; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01085055; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01085056; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01085057; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01085058; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A287CYS6; -.
DR STRING; 43179.ENSSTOP00000026409; -.
DR Ensembl; ENSSTOT00000042885.1; ENSSTOP00000026409.1; ENSSTOG00000029587.1.
DR GeneTree; ENSGT00940000153998; -.
DR InParanoid; A0A287CYS6; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0001673; C:male germ cell nucleus; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR GO; GO:0044727; P:epigenetic programing of male pronucleus; IEA:Ensembl.
DR GO; GO:2000143; P:negative regulation of DNA-templated transcription initiation; IEA:Ensembl.
DR GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR GO; GO:0032197; P:retrotransposition; IEA:Ensembl.
DR GO; GO:0141005; P:retrotransposon silencing by heterochromatin formation; IEA:Ensembl.
DR GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR CDD; cd16931; HATPase_MORC-like; 1.
DR Gene3D; 3.30.40.100; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR041006; Morc_S5.
DR InterPro; IPR011124; Znf_CW.
DR PANTHER; PTHR23337:SF6; MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 1; 1.
DR PANTHER; PTHR23337; ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF17942; Morc6_S5; 1.
DR Pfam; PF07496; zf-CW; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS51050; ZF_CW; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00454}.
FT DOMAIN 477..531
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT REGION 699..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 282..352
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 702..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 871 AA; 99008 MW; BBF135675C25EF86 CRC64;
MSHKYATLRR AQLHLDFIHA NSTTHSFLFG ALAELLDNAR DSGAARLDVF SVDNEKLQGG
FMLCFLDDGC GMSPEEASDI IYFGTSKKRL STLKFIGQYG NGLKSGSMRI GKDFILFTKK
EETMTCVFFS QTFCEGEGLS EVVVPMPSWL TRTRDSVTDD PQKFSTELSI IYKYSPFKNE
AELMQQFDVI YGKCGTLLVI YNLKLLLSGE PELDVKTDKE DILMAGADED FPERWSFRAY
TSVLYFDPWM RIFIQAKRVQ TKHLCYCLYQ PRKYLYVTCS FKGTLKNEVK KAEEAVKIAE
LSLKEAQIKV NQPDITSSSS AKDILQKALE DVEAKRKNLK EKQRELKKAR TLFLFFGVNI
ENRSRAGMFI YSNNRLIKMH EKVGPQLKLK SLLGAGVVGI VNIPLEIMEP SHNKQEFLNV
QEYNHLLKVM GQYLVQYCKD TGLSNRNLTS FWNEFGYQRS KDMETSLDSL QYQRRQAMAI
PFMVQCDLCL KWRVLPSSMN YQEKEFHDMW ICANNPNLLE NSCRQVERLP CIPLGTMSTV
LPSKNEKEKQ LRESVLRYQN KLAEQQSQVT SRIAEFTPTC LTSTLKENTK TQKIRPSGVD
LKHESLSPIE LSVGQRSQKR NTEQTDCDVE YVSDYKTMKR SVPKKMKPLL QRHTVPENIQ
LAEPSQVIFQ VLDKSSPDVS LKQEQKEVPL INEEKQELCS DTPAIKRNSS FPNQESSSCV
TMEDLNPISG HEAKVSVSDG CKVASSLVTS SQSTIVKETA RKLMSNLREV LLYFFPEYQL
PSVFDCTSAE ELRASSELDQ CPEQTNKKLK ICFNQVSLSS RRLSGVCPGN VSKLLAAFPG
VSIASLFQGG PAEDLEQIDV YLEALLKEDN L
//
