ID   A0A287CZC7_ICTTR        Unreviewed;       772 AA.
AC   A0A287CZC7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
OS   Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS   tridecemlineatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC   Xerinae; Marmotini; Ictidomys.
OX   NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000026662.1, ECO:0000313|Proteomes:UP000005215};
RN   [1] {ECO:0000313|Proteomes:UP000005215}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Assembly & Analysis Group;
RG   Computational R&D Group;
RG   and Sequencing Platform;
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT   "The Draft Genome of Spermophilus tridecemlineatus.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSTOP00000026662.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC       ECO:0000256|RuleBase:RU000394}.
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DR   EMBL; AGTP01057026; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A287CZC7; -.
DR   STRING; 43179.ENSSTOP00000026662; -.
DR   Ensembl; ENSSTOT00000021020.2; ENSSTOP00000026662.1; ENSSTOG00000021156.2.
DR   GeneTree; ENSGT00940000158533; -.
DR   InParanoid; A0A287CZC7; -.
DR   Proteomes; UP000005215; Unassembled WGS sequence.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   CDD; cd01375; KISc_KIF9_like; 1.
DR   Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR   InterPro; IPR027640; Kinesin-like_fam.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47968; CENTROMERE PROTEIN E; 1.
DR   PANTHER; PTHR47968:SF36; CENTROMERE-ASSOCIATED PROTEIN E; 1.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00283}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Microtubule {ECO:0000256|RuleBase:RU000394};
KW   Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW   ECO:0000256|RuleBase:RU000394};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT   DOMAIN          6..324
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000259|PROSITE:PS50067"
FT   REGION          466..562
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          333..360
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        504..519
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        524..551
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         93..100
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   772 AA;  87476 MW;  70CB482400BAC77F CRC64;
     MGTRKKVHAF VRVKPTDDFA HEMIRYGDDN KSIDIHLKKD IRKGVVNNQQ TDWSFKLDGV
     LHDASQDLVY ETVAKDVVSQ ALDGYNGTIM CYGQTGAGKT YTMTGQVFKM IEERPTHAIT
     VRVSYLEIYN ESLFDLLSTL PYVGPSVTPM TIVENPQGVF IKGLSVHLTS QEEDAFSLLF
     EGETNRIIAS HMMNKNSSRS HCIFTIYMEA HSRTLSDEKY VTSKINLVDL AGSERLGKSG
     SEGRVLKEAT YINKSLSFLE QAIIVLGDHK RDHIPFRQWK LTHALKDSLG GNCNMVLVTN
     IYGEAAQLEE TLSLLRFASR MKLVTTEPAI NEKYNAERMV KNLEKELVLL KQELAIHDSL
     ANRNIVTYDP MDEIQIAEIN SQVRRYLEGT LDEIDIINLR QIQEVFNQFW VVLSQQEQEV
     EAALRRKYTL IDKNDFATIS AVQKAGIIDV NGHLVGEPDG QGFGLGVAPF STKPAKKSKS
     KKTVKDPPSS SARKEGASSP VSGKDLDMIS TSKTQLVPSS KDGDVKDVLS RDRETSSIEP
     LPSDSPKEES RPLRPTTPPS KLMAFEDFKN ERGSEINRIF KENKSILNER RKRASETTQH
     INVIKREIDV TKEALNSQKS LREKQGEYEN KGLMIIDEEE FLLILKLKDL KKQYRSEYQD
     LRDLRAEIQY CQHLVDQCRH RLLMEFDIWY NESFVIPEDM QVALKLGSSI GPGMVPVSRI
     VSLGEDDQDN FAQLQQTVLP EGPDAISFYN AKIKTEQKHN YLKTIMGLQQ TH
//