ID A0A287D075_ICTTR Unreviewed; 2824 AA.
AC A0A287D075;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Bromodomain PHD finger transcription factor {ECO:0000313|Ensembl:ENSSTOP00000026991.1};
GN Name=BPTF {ECO:0000313|Ensembl:ENSSTOP00000026991.1};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000026991.1, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000026991.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01052632; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01052633; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01052634; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01052635; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01052636; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01052637; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSSTOT00000039511.1; ENSSTOP00000026991.1; ENSSTOG00000013363.3.
DR GeneTree; ENSGT00940000154830; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0016589; C:NURF complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd05509; Bromo_gcn5_like; 1.
DR CDD; cd15559; PHD1_BPTF; 1.
DR CDD; cd15560; PHD2_3_BPTF; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR038028; BPTF.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45975; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR PANTHER; PTHR45975:SF2; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF00628; PHD; 2.
DR Pfam; PF15613; WSD; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS01359; ZF_PHD_1; 2.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 100..160
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 250..297
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2645..2696
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2722..2792
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 778..799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 843..914
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 989..1139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1164..1218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1260..1325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1392..1491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1763..1792
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1949..1968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2019..2055
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2140..2328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2493..2512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2561..2636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1812..1839
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2399..2429
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..47
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..89
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..487
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..524
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..554
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 852..914
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1050..1067
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1083..1097
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1164..1183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1199..1218
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1274..1290
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1299..1315
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1397..1431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1460..1489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2140..2186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2187..2201
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2202..2328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2493..2509
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2578..2604
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2612..2636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2824 AA; 314677 MW; 8E2D4EEA7110FF82 CRC64;
EEEEEEEEDG DAEETQDSEE EEEDEMEEDE DDSDYPEEME DDDDDASYCT ESSFRSHSTY
SSTPGRRKPR VHRPRSPILE EKDIPPLEFP KSSEDLMVPN EHIMNVIAIY EVLRNFGTVL
RLSPFRFEDF CAALVSQEQC TLMAEMHVVL LKAVLREEDT SNTTFGPADL KDSVNSTLYF
IDGMTWPEVL RVYCESDKEY HHVLPYQEAE DYPYGPVENK IKVLQFLVDQ FLTTNIAREE
LMSEGVIQYD DHCRVCHKLG DLLCCETCSA VYHLECVKPP LEEVPEDEWQ CEVCVAHKVP
GVTDCVAEIQ KNKPYIRHEP IGYDRSRRKY WFLNRRLIIE EDTENENEKK IWYYSTKVQL
AELIDCLDKD YWEAELCKIL EEMREEIHRH MDITEDLTNK ARGSNKSFLA AANEEILECI
RAKKGEIDNV KSPEEIEKEK NENENNSSKD AEKSREEFED QSLEKDDDDR TPNDDPEQGK
SEEESNKTCD SSNTSATTTS IQPNLENSNS SSELNSSQSE SAKAADDPEN GERESHTPVS
IQEEIGDFRS EKSNGEMSES LGAGRGASGS TRIITRLRNP DSKLSQLKSQ QVAAAAHEAN
KLFKEGKEVL VVNSQGEISR LSTKKEVVMK GNINNYFKLG QEGKYRVYHN QYSTNSFALN
KHQHREDHDK RRHLAHKFCL TPAGEFKWNG SVHGSKVLTI STLRLTITQL ENNIPSSFLH
PNWASHRANW IKAVQMCSKP REFALALAIL ECAVKPVVML PIWRESLGHT RLHRMTSIER
EEKEKVKKKE KKQEEEETMQ QATWVKYTFP VKHQYRVTGY GGWSWISKTH VYRFVPKLPG
NTNVNYRKSL EGTKNSMDEN MDESDKRKSP RSPKKIKADP DSEKAEVKDG DAAKGTDQSE
MEISKSTEKK DQDVKELLYS DIDKSFKEEP MEIDDDVKTE SQINCQESSQ VDVVNVSEGF
HLRTSYKKKI KSSKLDGLLE RRIKQFTLEE KQRHEKMKLE GGMKGPGKPS QSSLKSLSES
PVITKAKEGC HSDLLRQEQS PGVGHDTAED WTQGCSQSDS SVLGISDPSL NRDKRHPKDQ
ALDDVSNQSP RMNYHKQNSI ENDIDENVSE PASKGQELGK IQTKGSDVFI DDSKPASTDD
IDTLIYKNKK PLIQGDNDTI VSSSKSALLP SVPKSTSDRD APSLSKASDF DGKLGCDSEY
NSTLENSSDT MSIQDSSEED MIVQNSNEGV SEQFITPEQG NESLEPLKCE FVSDKSTGNC
DDRLQGKVTE TNGKKTSQQH KLEERPVNKC IDQINLKNIT DKRNSENRES EKKSQKTSTF
QINGKDNKPK VCLKGECLKE VSESKIISGN VEPKVNNINK IIPENDIKSL TVKQSGVKPF
INGDVIMEDF NEKNNSDTKS RVLSSSAGAG NYQDSLEALP SSTKESDSTE PPSPLPSCPG
SSSFNQVEDM EIEASEVKKV TPSPITSEEE SNLSSDFIDE NGLSSNKDEN VNGEAKRKTV
ITEVTTMTST VATESKTVIK VAKGDKQTVV SSTENCAKST VTTTTTVTKL STPSTGSSVD
IISVKEQSKT VVTTTVTDSL TTAGGTLVTS MTVSKEYSTR DKVKLMKFSR PKKTRSGTAL
PSYRKFITKS SKKSIFVLPN DDLKKLARKG GIREVPYFNY NAKPALDIWP YPSPRPTFGI
TWRYRLQTVK SLAGVSLMLR LLWASLRWDD MAAKAPPGGG TTRTETSEME ITTTEIIKRR
DVGPYGIRSE YCIRKIICPI GVPEAPKETP TPQRKGLRSS ALRPKRPETP KQTGPVIIET
WVAEEELELW EIRAFAERVE KEKAQAVEQQ AKKRLEQQKP TVIAASTTSP TNSTTSTISP
AQKVMVAPIS GSVTTGTKMV LTTKVGSPAT VTFQQNKNFH QTFATWVKQG QSNSGVVQVQ
QKVLGIIPSS TGTSQQTFTS FQPRTATVTI RPNTSGSGGT TSTSQVITGP QIRPGMTVIR
TPLQQSTLGK AIIRTPVMVQ PGTPQQVVTQ IIRGQPVSTA ISAPSPASST PGQKGASTAS
LQAPTPQSPR PQQGQVKLTM AQLTQLTQGH GGNQGLTVVI QGQGQTTGQL QLIPQGVTIL
PGPGQQLMQA AMPNGTVQRF LFTPLATTAT AASTTTTTVS SAAAGSGEQK QNKSSPQTQV
QQAKTLPPAQ SSSVSPAEAQ PQTAQPSAQP QPQPQPQPQS PTQPETQTTV ASHVPSEAQP
TQAQSSKPQV ASQCQPQSNA QGQSPVRVQS PPQTRIRPST PSQVSPGQQS QVQTTTSQPI
PIQPHTSLQI PSQGQPQSQP QVQSSTQTLS SGQTLNQVTV SSPSRPQLQI QQPQPQVIAV
PQLQQQVQVL SQIQSQVVAQ IQAQQGGVPQ QIKLQLPIQI QQSSAVQTHQ IQNVVTVQAA
SVQEQLQRVQ QLRDQQQKKK QQQIEIKREH TLQASNQSEI IQKQVVMKHN AVIEHLKQKK
TMTPAEREEN QRMIVCNQVM KYILDKIDKE EKQAAKKRKR EESVEQKRSK QNATKLSALL
FKHKEQLKAE ILKKRALLDK DLQIEVQEEL RRDLKMKKEK DMMQAVQASA VAAPSPPASV
ATAPPAPPPS PPAAPPPQHS ALLPTPPLPA ASQKRKREEE KDSSSKSKKK KMISTTSKET
KKDTKLYCIC KTPYDESKFY IGCDRCQNWY HGRCVGILQS EAELIDEYVC PQCQSTEDAM
TVLTPLTEKD YEGLKRVLRS LQAHKMAWPF LEPVDPNDAP DYYGVIKEPM DLATMEERVQ
RRYYEKLTEF VADMTKIFDN CRYYNPSDSP FYQCAEVLES FFVQKLKGFK ASRSHNNKLQ
STAS
//
