ID A0A287D315_ICTTR Unreviewed; 521 AA.
AC A0A287D315;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cell division cycle 45 {ECO:0000313|Ensembl:ENSSTOP00000027917.1};
GN Name=CDC45 {ECO:0000313|Ensembl:ENSSTOP00000027917.1};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000027917.1, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000027917.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CDC45 family.
CC {ECO:0000256|ARBA:ARBA00010727}.
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DR EMBL; AGTP01078113; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01078114; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005334589.1; XM_005334532.1.
DR AlphaFoldDB; A0A287D315; -.
DR Ensembl; ENSSTOT00000040192.1; ENSSTOP00000027917.1; ENSSTOG00000002917.3.
DR GeneTree; ENSGT00390000009662; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR InterPro; IPR003874; CDC45.
DR PANTHER; PTHR10507; CDC45-RELATED PROTEIN; 1.
DR PANTHER; PTHR10507:SF0; CELL DIVISION CONTROL PROTEIN 45 HOMOLOG; 1.
DR Pfam; PF02724; CDC45; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT REGION 91..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..119
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 521 AA; 60270 MW; 3761697F41CBFEE7 CRC64;
MFVSDFRKEF YELVQSQRVL LFVASDVDAL CACKILQALF QCDHVQYTLV PVSGWQELET
AFLEHKEQIK LLIKQDDDLE VPAYDDIFRD EEEEDEEHSG NDSDGSEPSE KRTRLEEEIV
QQTMKRRQRR EWEARRRDIL FDYEQYEYHG TSSAMVMFDL AWMMSKDLND MLWWAIVGLT
DQWIQDKITQ MKYVTDVGIL QRHVSRHNHR NEDEENTLSV DCTRISFEYD LRLVLYQHWS
LHDSLCNTSY TAARFKLWSV HGQKRLQEFL ADMGLPLKQV KQKFQSMDIS LKENLREMIE
ESANKFGMKD MRVQTFSIHF GFKHKFLASD VVFATMSLME SPEKDSSGTD HFIQALDSLS
RSNLDKLYLG LELAKKQLRA TQQTIASCLC TNLVISQGPF LYCSLMEGTP DVMLFSKPAS
LSLLSKHLLK SFVCSTKNRR CKLLPLVMAA PLSIEQGTVT VVGIPPETDG SDRKNFFGRA
FEKAAESTSS RTLHNHFDLS VIELKAEDRS KFLDALVSLL S
//
