ID A0A287D8K9_ICTTR Unreviewed; 524 AA.
AC A0A287D8K9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=SEC24 homolog D, COPII coat complex component {ECO:0000313|Ensembl:ENSSTOP00000029869.1};
GN Name=SEC24D {ECO:0000313|Ensembl:ENSSTOP00000029869.1};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000029869.1, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000029869.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; AGTP01114080; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01114081; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01114082; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01114083; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A287D8K9; -.
DR Ensembl; ENSSTOT00000039372.1; ENSSTOP00000029869.1; ENSSTOG00000014719.3.
DR eggNOG; KOG1984; Eukaryota.
DR GeneTree; ENSGT00950000182924; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR13803:SF6; PROTEIN TRANSPORT PROTEIN SEC24D; 1.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 4: Predicted;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 1..172
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 178..261
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 274..373
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT DOMAIN 393..466
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
SQ SEQUENCE 524 AA; 58201 MW; 7716EBF813434B92 CRC64;
MVVTDIGEVF VPLLDGFLVN YQESQSVIHN LLDQIPGMFA DSNENEAVFA PVVQAGMEAL
KAAECPGKLF IFHSSLPTAE APGKLKNRDD KRLLNTDKEK ILFQPQTSVY EALAKDCVAH
GCSVTLFLFP SQYVDVASLG LVPLLTGGTL YKYSNFQMHL DSQQFLNDLR SDVEKKIGFD
AIMRVRTSTG FRATDFFGGV FMNNTTDVEM AALDCDKAVT VEFKHDDRLS EDSGALIQCA
VLYTTIGGQR RLRIHNLGLN CSSQLADLYK SCETDALINF FAKSAFKAVL HQPLKVIREI
LVNQTAHMLA CYRKNCASPS AASQLILPDS MKILPVYMNS LLKSCVLLSR PDTPTDERAF
QRQLVMTMGV ADSQLFFYPQ FLPIHTLDVK STALPAAVRC SESRLSEGGI FLLANGLNMF
LWLGVSSPPE LIQGIFNVPS FAHVSTDMTV LPEVGSPHSR QLRMIMGVIQ QKRPYSMKLT
IVKQREQPEM VFRQLLVEDR GLHGGSSYVD FLCCVHKEIC QLLS
//
