ID   A0A287DB43_ICTTR        Unreviewed;      1084 AA.
AC   A0A287DB43;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=C2 calcium dependent domain containing 5 {ECO:0000313|Ensembl:ENSSTOP00000030749.1};
GN   Name=C2CD5 {ECO:0000313|Ensembl:ENSSTOP00000030749.1};
OS   Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS   tridecemlineatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC   Xerinae; Marmotini; Ictidomys.
OX   NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000030749.1, ECO:0000313|Proteomes:UP000005215};
RN   [1] {ECO:0000313|Proteomes:UP000005215}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Assembly & Analysis Group;
RG   Computational R&D Group;
RG   and Sequencing Platform;
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT   "The Draft Genome of Spermophilus tridecemlineatus.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSTOP00000030749.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AGTP01054932; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A287DB43; -.
DR   STRING; 43179.ENSSTOP00000030749; -.
DR   Ensembl; ENSSTOT00000037124.1; ENSSTOP00000030749.1; ENSSTOG00000004906.3.
DR   eggNOG; KOG1031; Eukaryota.
DR   GeneTree; ENSGT00390000000212; -.
DR   InParanoid; A0A287DB43; -.
DR   Proteomes; UP000005215; Unassembled WGS sequence.
DR   GO; GO:0005938; C:cell cortex; IEA:Ensembl.
DR   GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:Ensembl.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0032587; C:ruffle membrane; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:Ensembl.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IEA:Ensembl.
DR   GO; GO:0031340; P:positive regulation of vesicle fusion; IEA:Ensembl.
DR   CDD; cd08688; C2_KIAA0528-like; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR037785; C2_C2CD5.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR038983; C2CD5.
DR   PANTHER; PTHR37412; C2 DOMAIN-CONTAINING PROTEIN 5; 1.
DR   PANTHER; PTHR37412:SF2; C2 DOMAIN-CONTAINING PROTEIN 5; 1.
DR   Pfam; PF00168; C2; 1.
DR   SMART; SM00239; C2; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   PROSITE; PS50004; C2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT   DOMAIN          1..109
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   REGION          265..330
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        273..319
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1084 AA;  119798 MW;  AFC95FBEFDDE5A38 CRC64;
     MPGKLKVKIV AGRHLPVMDR ASDLTDAFVE VKFGNTTFKT DVYLKSLNPQ WNSEWFKFEV
     DDEDLQDEPL QITVLDHDTY SANDAIGKVY IDIDPLLYSE AATVISGWFP IYDTIHGIRG
     EINVVVKVDL FNDLNRFRQS SCGVKFFCTT SIPKCYRAVI IHGFVEELVV NEDPEYQWID
     RIRTPRASNE ARQRLISLMS GELQRKIGLK VLEMRGNAVV GYLQCFDLEG ESGLVVRAIG
     TACTLDKLSS PAAFLPACNS PSKEMKEIPF NEDPNPNTHS SGPSTPLKNQ TYSFSPSKSY
     SRQSSSSDTD LSLTPKTGMG SGSAGKEGGP FKALLRQQTQ SALEQRGGSP HRFCRRREFP
     FFTLTTFPPG FLVHVGGVVS ARSVKLLDRI HNPAFVGIMG NTRSYKLLDW NSFNSDEPET
     RDAWWAEIRQ EIKSHAKALG CHAVVGYSES TSICEEVCIL SASGTAAVLN PRFLQDGTVE
     GCLEQRLEEN LPAGCGFCHI PYDELNMPFP AHLTYCYSCR KQKVPDVLFT TIDLPIDAIV
     IGKGCLIQAR LCRLKKKAQA EANATAISNL LPFMEYEVHT QLMNKLKLKG MNALFGLRIQ
     ITVGENMLMG LASATGVYLA ALPMPGGIQI AGKTPNDGSY EQHISHMQKK INDTIAKNKE
     LYEINPPEIS EEIIGSPIPE PRQRSRLLRS QSESSDEVME LDLSHGKKDA FVLEIDDTDA
     MEDVHSLLTD VPPPSGFYSC NTEIMPGINN WTSEIQMFTS VRVIRLSSLN LTNQALNKNF
     NDLCENLLKS LYFKLRSMIP CCLCHVNFTV SLPEDELIQV TVTAVAITFD KNQALQTTKP
     HVEKSLQRAS TDNEELLQFP LELCSDSLPS HPFPPAKEHL ESASSNSGIP AAQRATSVDY
     SSFADRCSSW IELIKLKAQT IRRGSIKTTV TLEKASPMGE GNFRNRSAPP CTNSTVGVVK
     MTPLSFIPGA KITKYLGIIN MFFIRETTSL REEGGVSGFL HAFIAEVFAM VRAHVAALGG
     NAVVSYIMKQ CVFMENPNKN QAQCLINVSG DAVIFVRESD LEVVSAQQPT ATCQPLCTGG
     DVTT
//