ID A0A287DB53_ICTTR Unreviewed; 99 AA.
AC A0A287DB53;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Transmembrane protein 14A {ECO:0000313|Ensembl:ENSSTOP00000030759.1};
GN Name=TMEM14A {ECO:0000313|Ensembl:ENSSTOP00000030759.1};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000030759.1, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000030759.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TMEM14 family.
CC {ECO:0000256|ARBA:ARBA00007590}.
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DR EMBL; AGTP01010644; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01010645; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005318623.1; XM_005318566.2.
DR AlphaFoldDB; A0A287DB53; -.
DR STRING; 43179.ENSSTOP00000030759; -.
DR Ensembl; ENSSTOT00000042144.1; ENSSTOP00000030759.1; ENSSTOG00000034800.1.
DR GeneID; 101960058; -.
DR CTD; 28978; -.
DR eggNOG; KOG4267; Eukaryota.
DR GeneTree; ENSGT00940000158206; -.
DR InParanoid; A0A287DB53; -.
DR OrthoDB; 5348983at2759; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:Ensembl.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:Ensembl.
DR GO; GO:1901029; P:negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IEA:Ensembl.
DR Gene3D; 6.10.250.1330; -; 1.
DR Gene3D; 1.10.10.1740; Transmembrane protein 14-like; 1.
DR InterPro; IPR005349; TMEM14.
DR InterPro; IPR044890; TMEM14_sf.
DR PANTHER; PTHR12668; TRANSMEMBRANE PROTEIN 14, 15; 1.
DR PANTHER; PTHR12668:SF11; TRANSMEMBRANE PROTEIN 14A; 1.
DR Pfam; PF03647; Tmemb_14; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 99 AA; 10781 MW; D40A421E01D283D3 CRC64;
MDLIGFGYAA LVTFGSILGY KRRGGLPSLI AGLFVGFLAA YGAYRVSMDK RDVKISLFTA
FFLATIMGVR FKRSKKIMPA GLVAGLSLMM ILRLVLLLL
//
