ID A0A287DEJ5_ICTTR Unreviewed; 619 AA.
AC A0A287DEJ5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Autophagy related 7 {ECO:0000313|Ensembl:ENSSTOP00000031936.1};
GN Name=ATG7 {ECO:0000313|Ensembl:ENSSTOP00000031936.1};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000031936.1, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000031936.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01073366; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01073367; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01073368; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01073369; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A287DEJ5; -.
DR Ensembl; ENSSTOT00000040461.1; ENSSTOP00000031936.1; ENSSTOG00000015288.3.
DR GeneTree; ENSGT00390000017509; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR CDD; cd01486; Apg7; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.140.70; Ubiquitin-like modifier-activating enzyme ATG7 N-terminal domain; 1.
DR InterPro; IPR032197; Atg7_N.
DR InterPro; IPR042522; Atg7_N_1.
DR InterPro; IPR045886; ThiF/MoeB/HesA.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR PANTHER; PTHR10953:SF3; UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7; 1.
DR Pfam; PF16420; ATG7_N; 2.
DR Pfam; PF00899; ThiF; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 9..133
FT /note="Ubiquitin-like modifier-activating enzyme Atg7 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF16420"
FT DOMAIN 134..280
FT /note="Ubiquitin-like modifier-activating enzyme Atg7 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF16420"
FT DOMAIN 296..556
FT /note="THIF-type NAD/FAD binding fold"
FT /evidence="ECO:0000259|Pfam:PF00899"
FT COILED 401..428
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 619 AA; 68465 MW; 0187BBB6034EC3E1 CRC64;
MGDPGLFKLQ FAPFSSALDV GFWHELTQKK LNEYRLDEAP KDIKGYYYNG DSAGLPARLT
LEFSAFDMNA PTPAHCCPAV GTLYNTNTLE SFKTADKKLL LEQAANEIWE SIKSGAALEN
PVFLNKFLLL TFAIQALERA YDDLCQTEGV TALPYFLIKY DDNMVRVSLL KHYSDFFQGQ
RIKITVGVYD PCNLAQYPGW PLRNFLVLAA HRWSSSFQSV EVLCFRDRTM QGARDIAHSI
IFEVKLPEMA FSPDCPKAVG WEKNQKGGMG PRMVNLSECM DPKRLAESSV DLNLKLMCWR
LVPTLDLEKV VSVKCLLLGA GTLGCNVART LMGWGVRHVT FVDNAKISYS NPVRQPLYEF
EDCLGGGKPK ALAAADRLQK IFPGVNARGF NMSIPMPGHP VNFSSITLEQ ARKDVEQLEQ
LIESHDVIFL LMDTRESRWL PAVIAASKRK LVINAALGFD TFVVMRHGLK KPKQQGAGDL
CPSHSVASAD LLGSSLFANI PGYKLGCYFC NDVVAPGDST RDRTLDQQCT VSRPGLAMIA
GALAVELMVS VLQHPEGGYA IASSSDDRMN EPPTSLGLVP HQIRGFLSRF DNVLPVSLAF
DKCTACSSKI WDMSDDETI
//
