ID A0A287DFA4_ICTTR Unreviewed; 755 AA.
AC A0A287DFA4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=MTSS I-BAR domain containing 1 {ECO:0000313|Ensembl:ENSSTOP00000032233.1};
GN Name=MTSS1 {ECO:0000313|Ensembl:ENSSTOP00000032233.1};
OS Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS tridecemlineatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC Xerinae; Marmotini; Ictidomys.
OX NCBI_TaxID=43179 {ECO:0000313|Ensembl:ENSSTOP00000032233.1, ECO:0000313|Proteomes:UP000005215};
RN [1] {ECO:0000313|Proteomes:UP000005215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Assembly & Analysis Group;
RG Computational R&D Group;
RG and Sequencing Platform;
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RT "The Draft Genome of Spermophilus tridecemlineatus.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSTOP00000032233.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGTP01001644; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01001645; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01001646; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGTP01001647; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005316224.1; XM_005316167.2.
DR AlphaFoldDB; A0A287DFA4; -.
DR Ensembl; ENSSTOT00000043067.1; ENSSTOP00000032233.1; ENSSTOG00000004442.3.
DR GeneID; 101959369; -.
DR CTD; 9788; -.
DR GeneTree; ENSGT00950000183156; -.
DR OrthoDB; 3875239at2759; -.
DR Proteomes; UP000005215; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd07643; I-BAR_IMD_MIM; 1.
DR CDD; cd22060; WH2_MTSS1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR030127; MTSS1/MTSS2.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR PANTHER; PTHR15708:SF10; PROTEIN MTSS 1; 1.
DR Pfam; PF08397; IMD; 1.
DR Pfam; PF02205; WH2; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51338; IMD; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005215}.
FT DOMAIN 1..250
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 727..744
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 140..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 427..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..634
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..670
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..701
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 755 AA; 82149 MW; 7084AF8833066D66 CRC64;
MEAVIEKECS ALGGLFQTII SDMKGSYPVW EDFINKAGKL QSQLRTTVVA AAAFLDAFQK
VADMATSTRG GTREIGSALT RMCMRHRSIE AKLRQFSSAL IDCLINPLQE QMEEWKKVAN
QLDKDHAKEY KKARQEIKKK SSDTLKLQKK AKKGRGDIQP QLDSALQDVN DKYLLLEETE
KQAVRKALIE ERGRFCTFIS MLRPVIEEEI SMLGEITHLQ TISEDLKSLT MDPHKLPSSS
EQVILDLKGS DYSWSYQTPP SSPSTTMSRK SSVCSSLNSV NSSDSRSSGS HSHSPSSHYR
YRSSNLAQQA PVRLSSVSSH DSGFISQDAF QSKSPSPMPP EATNQLSNGF SHYSLSSESH
VGPVGAGPFP HCLPASRLLP RVTSVHLPDY AHYYTIGPGM FPSSQIPSWK DWAKPGPYDQ
PLVNTLQRRR EKREPDPSGG GPPPSGGPPA AAEEAQRPRS MTVSAATRPG EEMEACEELA
LALSRGLQLD TQRSSRDSLQ CSSGYSTQTT TPCCSEDTIP SQVSDYDYFS VSGDQEADQQ
EFDKSSTIPR NSDISQSYRR MFQAKRPAST AGLPTTLGPA MVTPGVATIR RTPSTKPSVR
RGTIGAGPIP IKTPVIPVKT PTVPDLPGVL PAPPDGPEER GEHSPESPSV GEGPQGVTSM
PSSMWSGQAS VNPPLPGPKP SIPEEHRQAI PESEAEDQER DPPSATVSPG QIAESDPADL
SPRDTPQGED MLNAIRRGVK LKKTTTNDRS APRFS
//
