GenomeNet

Database: UniProt
Entry: A0A287NEA7_HORVV
LinkDB: A0A287NEA7_HORVV
Original site: A0A287NEA7_HORVV 
ID   A0A287NEA7_HORVV        Unreviewed;       639 AA.
AC   A0A287NEA7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   08-MAY-2019, entry version 11.
DE   RecName: Full=DNA polymerase {ECO:0000256|RuleBase:RU000442};
DE            EC=2.7.7.7 {ECO:0000256|RuleBase:RU000442};
OS   Hordeum vulgare subsp. vulgare (Domesticated barley).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX   NCBI_TaxID=112509 {ECO:0000313|EnsemblPlants:HORVU4Hr1G017480.4, ECO:0000313|Proteomes:UP000011116};
RN   [1] {ECO:0000313|EnsemblPlants:HORVU4Hr1G017480.4, ECO:0000313|Proteomes:UP000011116}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=subsp. vulgare {ECO:0000313|Proteomes:UP000011116};
RX   PubMed=23075845; DOI=10.1038/nature11543;
RG   The International Barley Genome Sequencing Consortium;
RT   "A physical, genetic and functional sequence assembly of the barley
RT   genome.";
RL   Nature 491:711-716(2012).
RN   [2] {ECO:0000313|EnsemblPlants:HORVU4Hr1G017480.4}
RP   IDENTIFICATION.
RC   STRAIN=subsp. vulgare {ECO:0000313|EnsemblPlants:HORVU4Hr1G017480.4};
RG   EnsemblPlants;
RL   Submitted (OCT-2017) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-
CC         COMP:11130, Rhea:RHEA-COMP:11131, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:61560, ChEBI:CHEBI:83828; EC=2.7.7.7;
CC         Evidence={ECO:0000256|RuleBase:RU000442};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|RuleBase:RU000442};
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU000442}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-B family.
CC       {ECO:0000256|RuleBase:RU000442}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EnsemblPlants; HORVU4Hr1G017480.4; HORVU4Hr1G017480.4; HORVU4Hr1G017480.
DR   Gramene; HORVU4Hr1G017480.4; HORVU4Hr1G017480.4; HORVU4Hr1G017480.
DR   Proteomes; UP000011116; Unassembled WGS sequence.
DR   ExpressionAtlas; A0A287NEA7; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.132.60; -; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   Gene3D; 3.90.1600.10; -; 1.
DR   InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR   InterPro; IPR017964; DNA-dir_DNA_pol_B_CS.
DR   InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR   InterPro; IPR042087; DNA_pol_B_C.
DR   InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR025687; Znf-C4pol.
DR   Pfam; PF00136; DNA_pol_B; 1.
DR   Pfam; PF14260; zf-C4pol; 1.
DR   PRINTS; PR00106; DNAPOLB.
DR   SMART; SM00486; POLBc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS00116; DNA_POLYMERASE_B; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|RuleBase:RU000442};
KW   Complete proteome {ECO:0000313|Proteomes:UP000011116};
KW   DNA replication {ECO:0000256|RuleBase:RU000442};
KW   DNA-binding {ECO:0000256|RuleBase:RU000442};
KW   DNA-directed DNA polymerase {ECO:0000256|RuleBase:RU000442};
KW   Iron {ECO:0000256|RuleBase:RU000442};
KW   Iron-sulfur {ECO:0000256|RuleBase:RU000442};
KW   Metal-binding {ECO:0000256|RuleBase:RU000442};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU000442};
KW   Nucleus {ECO:0000256|RuleBase:RU000442};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011116};
KW   Transferase {ECO:0000256|RuleBase:RU000442};
KW   Zinc {ECO:0000256|RuleBase:RU000442};
KW   Zinc-finger {ECO:0000256|RuleBase:RU000442}.
FT   DOMAIN       79    512       DNA_pol_B. {ECO:0000259|Pfam:PF00136}.
FT   DOMAIN      549    620       zf-C4pol. {ECO:0000259|Pfam:PF14260}.
SQ   SEQUENCE   639 AA;  72017 MW;  0C7F5BDC8B311845 CRC64;
     MQRDYKLSSY SLNSVSAHFL GEQKEDVHHS IISDLQNGNS ETRRRLAVYC LKDAYLPQRL
     LDKLMYIYNY VEMARVTGVP ISFLLSRGQS IKVLSQLLRK AKQRNLVIPN IKGQSSGQDT
     FEGATVLEAR AGFYEKPIAT LDFASLYPSI MMAHNLCYCT LVPPEDVRKH NLPPESLYKT
     PSGEIFVKPE LQKGILPEIL EELLAARKRA KADLKEAKDP FERAVLDGRQ LALKISANSV
     YGFTGATVGQ LPCLEISSSV TSYGRQMIEH TKKLVEDKFT TVGGYEHNAE VIYGDTDSVM
     VQFGVSTVKD AMKLGREAAE YISGTFIKPI KLEFEKVYFP YLLISKKRYA GLYWTNPEKF
     DKMDTKGIET VRRDNCLLVK NLVTECLHKI LVDRDVPGAV QYVKNTISDL LMNRVDLSLL
     VITKGLTKTG EDYAVKAAHV ELAERMRKRD AATAPTVGDR VPYVIIKAAK GAKAYEKSED
     PIYVLDNNIP IDPQYYLENQ ISKPLLRIFE PILKNASREL LHGSHTRAVS ISTPSNSGIM
     KFAKKQLTCL GCKAVISGPN QTLCSHCKGR EAELYCKTVA NVSDLEMLFG KLWTQCQECQ
     GSLHQDVLCT SRDCPIFYRR RKAQKDMAEA RVQLDRWDF
//
DBGET integrated database retrieval system