ID A0A287NLV3_HORVV Unreviewed; 342 AA.
AC A0A287NLV3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 08-NOV-2023, entry version 18.
DE RecName: Full=glutamine--fructose-6-phosphate transaminase (isomerizing) {ECO:0000256|ARBA:ARBA00012916};
DE EC=2.6.1.16 {ECO:0000256|ARBA:ARBA00012916};
OS Hordeum vulgare subsp. vulgare (Domesticated barley).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX NCBI_TaxID=112509 {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.4HG0356380.1, ECO:0000313|Proteomes:UP000011116};
RN [1] {ECO:0000313|Proteomes:UP000011116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Morex {ECO:0000313|Proteomes:UP000011116};
RX PubMed=23075845; DOI=10.1038/nature11543;
RG The International Barley Genome Sequencing Consortium;
RA Mayer K.F., Waugh R., Brown J.W., Schulman A., Langridge P., Platzer M.,
RA Fincher G.B., Muehlbauer G.J., Sato K., Close T.J., Wise R.P., Stein N.;
RT "A physical, genetic and functional sequence assembly of the barley
RT genome.";
RL Nature 491:711-716(2012).
RN [2] {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.4HG0356380.1}
RP IDENTIFICATION.
RC STRAIN=subsp. vulgare
RC {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.4HG0356380.1};
RG EnsemblPlants;
RL Submitted (JAN-2022) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-
CC phosphate + L-glutamate; Xref=Rhea:RHEA:13237, ChEBI:CHEBI:29985,
CC ChEBI:CHEBI:58359, ChEBI:CHEBI:58725, ChEBI:CHEBI:61527; EC=2.6.1.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001031};
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DR AlphaFoldDB; A0A287NLV3; -.
DR EnsemblPlants; HORVU.MOREX.r3.4HG0356380.1; HORVU.MOREX.r3.4HG0356380.1; HORVU.MOREX.r3.4HG0356380.
DR Gramene; HORVU.MOREX.r3.4HG0356380.1; HORVU.MOREX.r3.4HG0356380.1; HORVU.MOREX.r3.4HG0356380.
DR Proteomes; UP000011116; Chromosome 4H.
DR ExpressionAtlas; A0A287NLV3; baseline.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR CDD; cd00714; GFAT; 1.
DR Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 1.
DR InterPro; IPR017932; GATase_2_dom.
DR InterPro; IPR047084; GFAT_N.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR InterPro; IPR046348; SIS_dom_sf.
DR PANTHER; PTHR10937; GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING; 1.
DR PANTHER; PTHR10937:SF16; GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING); 1.
DR Pfam; PF13522; GATase_6; 1.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51278; GATASE_TYPE_2; 1.
PE 4: Predicted;
KW Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962};
KW Reference proteome {ECO:0000313|Proteomes:UP000011116};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 2..275
FT /note="Glutamine amidotransferase type-2"
FT /evidence="ECO:0000259|PROSITE:PS51278"
SQ SEQUENCE 342 AA; 37941 MW; B0D4133FB9AE7D44 CRC64;
MCGIFAYLNY CAPRDRRYVL EVLLNGLRRL EYRGYDSSGI ALDADLPPPG SAAAYAGAPP
LVFREEGKID NLVRSVYSEV DEKGVNLDAT FSVHAGIAHT RWATHGVPAP KNSHPQSSGA
GDEFLVVHNG IITNYEILKE TLVRHGFTFE SDTDTEVIPK LAKSVFDQAR DGEGDMTFSQ
VVMEVMRQLE GAYALIFKSP HYPNELITCK QGSTLILGVN EVSDQNSVKS FQNVKSLTTN
GNPMEFFSSD LCAIVEHTKN YLAIEDNEII HIKDGSVSIL KFDKEKEKPA SVQRALSVLE
MEVEQIKKGS YDHFMQKEIH EQPHSLTTTM RGRLKDSGVV LG
//
