ID   A0A290XCM5_9GAMM        Unreviewed;       500 AA.
AC   A0A290XCM5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Tryptophan halogenase {ECO:0000313|EMBL:ATD66738.1};
GN   ORFNames=CNR27_04160 {ECO:0000313|EMBL:ATD66738.1};
OS   Luteimonas chenhongjianii.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Luteimonas.
OX   NCBI_TaxID=2006110 {ECO:0000313|EMBL:ATD66738.1, ECO:0000313|Proteomes:UP000218968};
RN   [1] {ECO:0000313|Proteomes:UP000218968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=100111 {ECO:0000313|Proteomes:UP000218968};
RA   Gui Z.;
RT   "Luteimonas liuhanmingii sp.nov., isolated from the intestinal contents of
RT   Tibetan Plateau Pika in Yushu, Qinghai Province, China.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP023406; ATD66738.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A290XCM5; -.
DR   KEGG; lum:CNR27_04160; -.
DR   OrthoDB; 462203at2; -.
DR   Proteomes; UP000218968; Chromosome.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006905; Flavin_halogenase.
DR   InterPro; IPR033856; Trp_halogen.
DR   PANTHER; PTHR43747; FAD-BINDING PROTEIN; 1.
DR   PANTHER; PTHR43747:SF4; FLAVIN-DEPENDENT TRYPTOPHAN HALOGENASE; 1.
DR   Pfam; PF04820; Trp_halogenase; 1.
DR   PIRSF; PIRSF011396; Trp_halogenase; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   FAD {ECO:0000256|PIRSR:PIRSR011396-2};
KW   Flavoprotein {ECO:0000256|PIRSR:PIRSR011396-2};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR011396-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218968}.
FT   ACT_SITE        83
FT                   /evidence="ECO:0000256|PIRSR:PIRSR011396-1"
FT   BINDING         18..21
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT   BINDING         83
FT                   /ligand="7-chloro-L-tryptophan"
FT                   /ligand_id="ChEBI:CHEBI:58713"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT   BINDING         332
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT   BINDING         341
FT                   /ligand="L-tryptophan"
FT                   /ligand_id="ChEBI:CHEBI:57912"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
FT   BINDING         345
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR011396-2"
SQ   SEQUENCE   500 AA;  56040 MW;  2AC7490351F74D99 CRC64;
     MQETPPNTAV RRVVIAGGGT AGWMAAAGIS RTLGPMLDIV LVESDEIPTV GVGEATIPTL
     VTFHRALGLD EREFMAATQA TFKLGIRFAD WKARGEEYVH SFGTTGKDHW SAGFQHFWHR
     GRSRGLAGDY GDYCLELRAA LEDRFAHLPE NGLNYAFHMD AGLYARYLRR FSESHGVRRI
     EGRIAEVQAD RASGNIEALV LASGERIEGD LFIDCTGFRG LLIEQALGVG YEDWSHWLLC
     DSAIAVQTAS VGPAVPYTRS TAREAGWQWR IPLQHRVGNG IVYASRYIDD AQARETLLAN
     LQGERLVEPR TIRFRPGQRE RTWHGNCVAL GLASGFLEPL ESTSIHLIQR GIIRLLQLFP
     AAGIRQTDVD EYNRQSREEI ESIRDFVILH YKVTDRDDTP FWRACREMQV PDSLAHRIAL
     FADSGRVFRE GFELFAENSW VQVMLGQGLV PRSHHPTADL MDDAELSRFL GQIRERVART
     LAQLPAHETY VRGYCPAAPV
//