ID A0A290XED0_9GAMM Unreviewed; 886 AA.
AC A0A290XED0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|ARBA:ARBA00021982, ECO:0000256|HAMAP-Rule:MF_00096};
GN Name=mutS {ECO:0000256|HAMAP-Rule:MF_00096,
GN ECO:0000313|EMBL:ATD67296.1};
GN ORFNames=CNR27_07460 {ECO:0000313|EMBL:ATD67296.1};
OS Luteimonas chenhongjianii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Luteimonas.
OX NCBI_TaxID=2006110 {ECO:0000313|EMBL:ATD67296.1, ECO:0000313|Proteomes:UP000218968};
RN [1] {ECO:0000313|Proteomes:UP000218968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=100111 {ECO:0000313|Proteomes:UP000218968};
RA Gui Z.;
RT "Luteimonas liuhanmingii sp.nov., isolated from the intestinal contents of
RT Tibetan Plateau Pika in Yushu, Qinghai Province, China.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|ARBA:ARBA00024647,
CC ECO:0000256|HAMAP-Rule:MF_00096}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|HAMAP-Rule:MF_00096,
CC ECO:0000256|RuleBase:RU003756}.
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DR EMBL; CP023406; ATD67296.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A290XED0; -.
DR KEGG; lum:CNR27_07460; -.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000218968; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 6.10.140.430; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00096; MutS; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00096}; Reference proteome {ECO:0000313|Proteomes:UP000218968}.
FT DOMAIN 712..728
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 638..645
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00096"
SQ SEQUENCE 886 AA; 97263 MW; 1612BD392564B279 CRC64;
MAGTRAPSQA RCRSEVRAND PSLQEHTPLM KQFFAAKAEH PDVLLFFRMG DFYELFYDDA
RKAARLLDIT LTQRGNSAGA PIPMAGVPHH ASEGYLARLV ALGESVAICE QIGDPAASKG
LVERKVVRIV TPGTVTDEAL LQERRDTLLM AVARQRNGQY GLAWADLAGG RFLVCECANE
DTLEAEIARL DPAELLVPDE DGWPAFLFER GGVRRRPPWL FDAESGRRQL LQFFGLHDLT
GFGIDDRPLA VAAAGALLGY VEETQKQRLP HLTSISVESG DGAIAMNAAT RRHLELDTRV
DGDTRNTLLG VLDSTITPMG GRLLRRWLHR PLRDRAVLDE RLHAVDTLQR SGADADLRER
FRALGDLERV LTRIALRSAR PRDLSTLRDG LAMLPDVRGI LGALDSPRLR TLHDGLGEHA
AEARLLADAL VEQPPVLARD GGVFADGHDA ELAELRRLST HADQFLVDLE ARERETSGIP
TLKVGYNRVH GYYIEVSKAH AARAPAHYTR RQTLTNAERY ITEELKQFED KVLSARERAL
ARERLLYEQL LDTLGGRLEA LKHCAGALSE LDVLACFAER AQALDWSRPQ LGAAPGICIE
RGRHPVVEAV RREPFEPNDL VLGDSDTFNE RRMLVITGPN MGGKSTYMRQ NALIVLLAHI
GSFVPASRAV IGPIDRILTR IGAGDDLAKG QSTFMVEMAE TSYILHHATD CSLVLMDEIG
RGTSTYDGLA LADACARHLA QRNRSYTLFA THYFELTALA QPGSGIANVH LDAVEHRDQQ
GNEKLVFMHA VKDGPADRSF GLQVAALAGL PRQVVRDARA RLAELEQRRH DSPASAPLSA
GTLDSPQQIG LFGPNSAAVE ALAGLDPDEL SPKQALEALY RIKALL
//
