ID A0A291GHW2_9MICO Unreviewed; 302 AA.
AC A0A291GHW2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:ATG50133.1};
GN ORFNames=CFK38_00285 {ECO:0000313|EMBL:ATG50133.1};
OS Brachybacterium vulturis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC Brachybacterium.
OX NCBI_TaxID=2017484 {ECO:0000313|EMBL:ATG50133.1, ECO:0000313|Proteomes:UP000218165};
RN [1] {ECO:0000313|Proteomes:UP000218165}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VM2412 {ECO:0000313|Proteomes:UP000218165};
RA Tak E.J., Bae J.-W.;
RT "Brachybacterium sp. VM2412.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP023563; ATG50133.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A291GHW2; -.
DR KEGG; brz:CFK38_00285; -.
DR OrthoDB; 5119743at2; -.
DR Proteomes; UP000218165; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR039538; BetI_C.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR Pfam; PF13977; TetR_C_6; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SMART; SM00530; HTH_XRE; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000218165};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 29..83
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT DOMAIN 113..173
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 136..155
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 302 AA; 32773 MW; DF165D63A8D33E15 CRC64;
MTAAGDTAET ASSSAEAASS SAEAVRVRVR SCIEESGLAQ REFARRIELE ETKLSKALKG
TRRFSPAELV RIATVGGVTV NWLVSGSDSA SGPAAVPTAA SLPRRGREAP EQGRRRQTIV
ETAWALFASR GLHAVKISEI AAEAGVSTAA VYHYFSGKRE LFEETLRYSV KLAFDRQVAS
LHLISGPRER LEHLISLQLP ADGARAQEFA IWLQAWSEVA VGAGSQQNHA FAYQRWYRTV
HDVLREGQEA GVVAAEPLED LTTQLTSLID GLGIKVLVGT ISVEQMASQI HRFLERLVVA
RP
//
