ID A0A291IR42_9MOLU Unreviewed; 312 AA.
AC A0A291IR42;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=1-phosphofructokinase {ECO:0000256|ARBA:ARBA00013596, ECO:0000256|RuleBase:RU369061};
DE Short=Fru1PK {ECO:0000256|RuleBase:RU369061};
DE EC=2.7.1.56 {ECO:0000256|ARBA:ARBA00012131, ECO:0000256|RuleBase:RU369061};
DE AltName: Full=Fructose 1-phosphate kinase {ECO:0000256|ARBA:ARBA00032802, ECO:0000256|RuleBase:RU369061};
GN Name=pfkB {ECO:0000313|EMBL:ATG97208.1};
GN Synonyms=lacC {ECO:0000313|EMBL:MCL8216521.1};
GN ORFNames=CP520_00310 {ECO:0000313|EMBL:ATG97208.1}, LD118_00103
GN {ECO:0000313|EMBL:MCL8216521.1};
OS Mesoplasma lactucae ATCC 49193.
OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales;
OC Entomoplasmataceae; Mesoplasma.
OX NCBI_TaxID=81460 {ECO:0000313|EMBL:ATG97208.1, ECO:0000313|Proteomes:UP000232227};
RN [1] {ECO:0000313|EMBL:ATG97208.1, ECO:0000313|Proteomes:UP000232227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=831-C4 {ECO:0000313|EMBL:ATG97208.1,
RC ECO:0000313|Proteomes:UP000232227};
RA Knight T.F., Rubinstein R., Citino T.;
RT "SPAdes assembly of the Mesoplasma lactucae genome.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MCL8216521.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 49193 {ECO:0000313|EMBL:MCL8216521.1};
RA Green E.A., Klassen J.;
RT "Mollicute symbiont genomes associated with the fungus-growing ant,
RT Trachymyrmex septentrionalis.";
RL Submitted (FEB-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the ATP-dependent phosphorylation of fructose-l-
CC phosphate to fructose-l,6-bisphosphate.
CC {ECO:0000256|RuleBase:RU369061}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + beta-D-fructose 1-phosphate = ADP + beta-D-fructose 1,6-
CC bisphosphate + H(+); Xref=Rhea:RHEA:14213, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:32966, ChEBI:CHEBI:138881,
CC ChEBI:CHEBI:456216; EC=2.7.1.56;
CC Evidence={ECO:0000256|ARBA:ARBA00000823,
CC ECO:0000256|RuleBase:RU369061};
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000256|ARBA:ARBA00010688, ECO:0000256|RuleBase:RU369061}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP023668; ATG97208.1; -; Genomic_DNA.
DR EMBL; JAKNSY010000001; MCL8216521.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A291IR42; -.
DR KEGG; mlac:CP520_00310; -.
DR OrthoDB; 9801219at2; -.
DR Proteomes; UP000232227; Chromosome.
DR Proteomes; UP001139645; Unassembled WGS sequence.
DR GO; GO:0008662; F:1-phosphofructokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR CDD; cd01164; FruK_PfkB_like; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR022463; 1-PFruKinase.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR017583; Tagatose/fructose_Pkinase.
DR NCBIfam; TIGR03168; 1-PFK; 1.
DR NCBIfam; TIGR03828; pfkB; 1.
DR PANTHER; PTHR46566:SF1; 1-PHOSPHOFRUCTOKINASE; 1.
DR PANTHER; PTHR46566; 1-PHOSPHOFRUCTOKINASE-RELATED; 1.
DR Pfam; PF00294; PfkB; 1.
DR PIRSF; PIRSF000535; 1PFK/6PFK/LacC; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU369061};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU369061};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU369061};
KW Reference proteome {ECO:0000313|Proteomes:UP000232227};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000535}.
FT DOMAIN 7..288
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 312 AA; 34716 MW; 6C88B752573CDF29 CRC64;
MIYTITLNPA IDHVIETKDF VLDETNYYQN DYQTIGGKGI NVAVLLNNLQ AQVNALGIMG
KDNSKVFLEK FKEINLHNNF IMFDGNTRTN YKIKDLDNNK ETELNGLGDS FDAHKFKDGM
EFLRKNLKAN DLVIASGSVP TSLPDGVYFQ IGELVEKKKA IFILDSSKKW SLEGIKAHPY
LIKPNLQEIC ELLKIEFRND YSLSDLENMI LEVRKLGARN ILVSMGGQGA LYFSENDELY
KVGIAKGKVV NSVGAGDSMV GGFAYGLVNN FSIEKTLQYA AASGGATAFS EWIGSKELIE
ELVPTIMIEK LK
//
