ID A0A291JIF3_9STAP Unreviewed; 253 AA.
AC A0A291JIF3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=S-formylglutathione hydrolase {ECO:0000256|ARBA:ARBA00012479};
DE EC=3.1.2.12 {ECO:0000256|ARBA:ARBA00012479};
GN ORFNames=BJD96_02640 {ECO:0000313|EMBL:ATH59315.1};
OS Staphylococcus nepalensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=214473 {ECO:0000313|EMBL:ATH59315.1, ECO:0000313|Proteomes:UP000217956};
RN [1] {ECO:0000313|EMBL:ATH59315.1, ECO:0000313|Proteomes:UP000217956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JS1 {ECO:0000313|EMBL:ATH59315.1,
RC ECO:0000313|Proteomes:UP000217956};
RA Nam Y.-D., Kang J., Chung W.-H.;
RT "Complete genome sequence of Staphylococcus nepalensis JS1.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + S-formylglutathione = formate + glutathione + H(+);
CC Xref=Rhea:RHEA:14961, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:15740, ChEBI:CHEBI:57688, ChEBI:CHEBI:57925; EC=3.1.2.12;
CC Evidence={ECO:0000256|ARBA:ARBA00000080};
CC -!- SIMILARITY: Belongs to the esterase D family.
CC {ECO:0000256|ARBA:ARBA00005622}.
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DR EMBL; CP017460; ATH59315.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A291JIF3; -.
DR KEGG; snl:BJD96_02640; -.
DR Proteomes; UP000217956; Chromosome.
DR GO; GO:0018738; F:S-formylglutathione hydrolase activity; IEA:InterPro.
DR GO; GO:0046294; P:formaldehyde catabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000801; Esterase-like.
DR InterPro; IPR014186; S-formylglutathione_hydrol.
DR PANTHER; PTHR10061; S-FORMYLGLUTATHIONE HYDROLASE; 1.
DR PANTHER; PTHR10061:SF0; S-FORMYLGLUTATHIONE HYDROLASE; 1.
DR Pfam; PF00756; Esterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
FT ACT_SITE 121
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR614186-1"
FT ACT_SITE 205
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR614186-1"
FT ACT_SITE 234
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR614186-1"
SQ SEQUENCE 253 AA; 29198 MW; 72ED67D80953F6E6 CRC64;
MAILSINYNS KTIGMHHHFM VVLPEDASYF NKEAQPKPLK TLLLLHGLSS DETSYMRYTS
IERYANEHQL AVIMPNADHS GYSNMVFGHK YYDYILEVFD YVHQILPLSH KREDNFIAGH
SMGGYGTIKY ALAEGHRFAK ACPLSAVFDA QAFMDYKWYD YSGEAIAGIS KNAKGNELDP
YYLVEQAMQQ HKAIPELLIM CGTEDELYED NKKFINYLDE KQVSYLFEDG LGAHDYAYWD
YAIKRAIQWF VEA
//
