ID   A0A291Q0V5_9ACTN        Unreviewed;       343 AA.
AC   A0A291Q0V5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Putative reductase {ECO:0000313|EMBL:ATL25371.1};
GN   ORFNames=KY5_0353 {ECO:0000313|EMBL:ATL25371.1};
OS   Streptomyces formicae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1616117 {ECO:0000313|EMBL:ATL25371.1, ECO:0000313|Proteomes:UP000221011};
RN   [1] {ECO:0000313|EMBL:ATL25371.1, ECO:0000313|Proteomes:UP000221011}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KY5 {ECO:0000313|EMBL:ATL25371.1,
RC   ECO:0000313|Proteomes:UP000221011};
RA   Holmes N.A., Devine R., Qin Z., Seipke R.F., Wilkinson B., Hutchings M.I.;
RT   "Complete Genome Sequence of Streptomyces formicae KY5, the formicamycin
RT   producer.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP022685; ATL25371.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A291Q0V5; -.
DR   KEGG; sfk:KY5_0353; -.
DR   Proteomes; UP000221011; Chromosome.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR   PANTHER; PTHR43245:SF49; HREPIB; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000221011}.
FT   DOMAIN          5..220
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   343 AA;  37099 MW;  6F763791A3430B26 CRC64;
     MKNAVVIGAT GQTGRATVRA LVEDGWSVTA ASRSGGRDER WPGDVREAVL DREDDAQLAG
     VLGDGVDLVV DMVAFTAAHA RQYAAFADRI GSAVVLSSGA VYADAQGRSF DTQGEPDGFP
     RYPVPIPESQ PTVAPGDATY GTRKIALERG LLALGDRLPV TLLRAGAIHG PYCRGPRELY
     FVQRNLDGRR TRVLAHGGRS RFHPVGVRTL AELVRLAAAR PGSRVLNAGD PEAPTVAEIG
     ASVDAVMGVE TETVLVEGEP PEPGVGLTMW SSAHPVVYDM AAAERELGYR PVTTYAASLE
     ETVRWLVDHL RERDWREAFP KLAANYDLFN YRAEDAWLAR REK
//