ID   A0A291Q2E3_9ACTN        Unreviewed;      1294 AA.
AC   A0A291Q2E3;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Siderophore biosynthesis non-ribosomal peptide synthetase modules, Bacillibactin synthetase component F {ECO:0000313|EMBL:ATL25930.1};
GN   ORFNames=KY5_0912 {ECO:0000313|EMBL:ATL25930.1};
OS   Streptomyces formicae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1616117 {ECO:0000313|EMBL:ATL25930.1, ECO:0000313|Proteomes:UP000221011};
RN   [1] {ECO:0000313|EMBL:ATL25930.1, ECO:0000313|Proteomes:UP000221011}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KY5 {ECO:0000313|EMBL:ATL25930.1,
RC   ECO:0000313|Proteomes:UP000221011};
RA   Holmes N.A., Devine R., Qin Z., Seipke R.F., Wilkinson B., Hutchings M.I.;
RT   "Complete Genome Sequence of Streptomyces formicae KY5, the formicamycin
RT   producer.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR   EMBL; CP022685; ATL25930.1; -; Genomic_DNA.
DR   KEGG; sfk:KY5_0912; -.
DR   Proteomes; UP000221011; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR   GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR   GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR   CDD; cd05930; A_NRPS; 1.
DR   CDD; cd19543; DCL_NRPS; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.980; -; 2.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR020802; PKS_thioesterase.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   InterPro; IPR001031; Thioesterase.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   Pfam; PF00668; Condensation; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   Pfam; PF00975; Thioesterase; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SMART; SM00824; PKS_TE; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS50075; CARRIER; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000221011}.
FT   DOMAIN          973..1048
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   1294 AA;  138337 MW;  77CAD690C7A9AFBB CRC64;
     MSAAHHEGSA RPAPLQQGLF FHTAYDPEGQ AVYTTQLTLD FEGLLRPDTL RAACRILLDR
     HDSLRSGFRT DAAGAPVRFL VPDVALEWRE MDVRTSDPAA RDAETVRAVE EERARPFDLA
     RPPLVRFLLV RADEGRWRFA LTNHHIILDG WSTSVLLDEL FDLYAQLREG HEPELFPAPA
     YGTYLDWLED TGTDAARAAW ADALEGIQGP TLVAPHAVGT VMPERILCTL PTGLGAALRE
     RARECGVTLN TVVQVAWGLV LHHVTGGDDV LFGMTVSGRT ADVEDIDTMV GLLINTLPAR
     VRLAPGDTVA EVLQRTQDAQ LDLFDHHHLG LTEIQRDAGF GALFDTTTAF ENYPVSGGAP
     ALGDAVLVGT GGFDATHYPL SLICTPGEEL GVRLDYRPDL FERAEAARIR DWFVRVLETI
     ADDPRRTVAS VSVLTPEERR RILLEWNDTA RPVSPTTLPA LIEARAARHP DSPAVAHAGR
     ELTYGELNRR ANRFARLLLA HGAGPETLVA LALPRTPDMV VAVLAALKAG AAYVPVDVRY
     PAGRIAQMLG GARPLVVVVD SGTGTGTGTD TRSRTGIVPP DGATLVVMDA EPVVRHTAAQ
     PSGDVTDAER PRPLLPRHPA YVIHTSGSTG TPKGVVIEHA NAVQLVATVE DQFGRAGMAR
     VLASTSLSFD VSILEIITTL ATGGSIELVD DLFALLERDS WQGSMLSGVP SAVASVLAGG
     DTRLAAREVV LGGEPIPRGL LREIRERVPG STVTNIYGPT EATTYATTWR DGGEPADTEP
     PIGRPVPNCQ AYVLDPWLQP VPVGLPGELY LAGAGVARGY LDRPALTAER FVACPFGAPG
     RRMYRTGDQV RLRPDGQLDF LGRLDGQVKI NGFRVEPGEV ESALLRHEWI AQAVVVARGE
     RADDRRLVAY VVAAPPGTAL DVAELRRFVG DRLPRHMVPS TVVQLPRFPL MPNGKLDRAA
     LPAPSYARST TRAPADDRER TLCALFAEVL GADRVGPDDG FFDLGGHSLL ATRLVSRVRA
     VLGAEISVRT LYEAPTPAAL AGRIDATAPA TGLDVLLPLR LAGGGPPLFC VHAASGLAWP
     YARLLPHLPA DLPVYGLQSP AVEAPGTGPL TPESMARDYA ARIRAVQPHG PYHLIGWSVG
     GNIAYAVAAE LTAAGQQVAF LGLLDSYPPD PGLLPDRDTM VRAILDGIGF AADGTPPEQL
     AALGERTVAG VRATARGALD VLRAAPPLAP GLDITHFRAT ADGPGPEPKS WQAFTGGRLT
     TYDIGCGHHR MLDPAPLTEI CAVLTDSWKG RASS
//