ID   A0A291Q664_9ACTN        Unreviewed;       363 AA.
AC   A0A291Q664;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   ORFNames=KY5_2262c {ECO:0000313|EMBL:ATL27280.1};
OS   Streptomyces formicae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1616117 {ECO:0000313|EMBL:ATL27280.1, ECO:0000313|Proteomes:UP000221011};
RN   [1] {ECO:0000313|EMBL:ATL27280.1, ECO:0000313|Proteomes:UP000221011}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KY5 {ECO:0000313|EMBL:ATL27280.1,
RC   ECO:0000313|Proteomes:UP000221011};
RA   Holmes N.A., Devine R., Qin Z., Seipke R.F., Wilkinson B., Hutchings M.I.;
RT   "Complete Genome Sequence of Streptomyces formicae KY5, the formicamycin
RT   producer.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP022685; ATL27280.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A291Q664; -.
DR   KEGG; sfk:KY5_2262c; -.
DR   Proteomes; UP000221011; Chromosome.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000313|EMBL:ATL27280.1};
KW   Hydrolase {ECO:0000313|EMBL:ATL27280.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000221011};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          30..329
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   363 AA;  38797 MW;  4228E099BE6D7EA0 CRC64;
     MTDETSVPFR AGREGYASFR IPAVVRTAHG TLLAFCEGRV GSQDDFGNID VVLKRSADGG
     RTWGPLQIVG KNGADLAGNP APVVLDTGRV LLVQVRNAAA ATEDAIRRGK VSAADGRRVW
     VQHSDDDGLT WSAPREITGQ VKKASWRWYA TTPGHAVQLS TGRVVVPANH SLPPSGTDTG
     TEGKYNGGHC LLSDDAGATW RIGYIDDNAN GYINVNETTA AELPDGRLYF NTRNDSPAPG
     TRADAHSLDG GRSLVKPFRP QACLTGPVVE GSVLQLRDPD VLLFSGPADP GFRALMTVRR
     SHDAGTTWET AHTVDGLPAA YSDLVRVDDD TVGLLYETGD FSAYETITFR RIPVPGLTGE
     TDE
//