ID   A0A291Q7H8_9ACTN        Unreviewed;       826 AA.
AC   A0A291Q7H8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Adenine/guanine phosphoribosyltransferase-related PRPP-binding proteins {ECO:0000313|EMBL:ATL27455.1};
GN   ORFNames=KY5_2437c {ECO:0000313|EMBL:ATL27455.1};
OS   Streptomyces formicae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1616117 {ECO:0000313|EMBL:ATL27455.1, ECO:0000313|Proteomes:UP000221011};
RN   [1] {ECO:0000313|EMBL:ATL27455.1, ECO:0000313|Proteomes:UP000221011}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KY5 {ECO:0000313|EMBL:ATL27455.1,
RC   ECO:0000313|Proteomes:UP000221011};
RA   Holmes N.A., Devine R., Qin Z., Seipke R.F., Wilkinson B., Hutchings M.I.;
RT   "Complete Genome Sequence of Streptomyces formicae KY5, the formicamycin
RT   producer.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP022685; ATL27455.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A291Q7H8; -.
DR   KEGG; sfk:KY5_2437c; -.
DR   Proteomes; UP000221011; Chromosome.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   CDD; cd06223; PRTases_typeI; 1.
DR   Gene3D; 3.40.50.2020; -; 1.
DR   InterPro; IPR028157; PELOTA_dom.
DR   InterPro; IPR000836; PRibTrfase_dom.
DR   InterPro; IPR029057; PRTase-like.
DR   InterPro; IPR041688; PRTase_2.
DR   InterPro; IPR011215; StiP_N.
DR   InterPro; IPR022537; TRSP_dom.
DR   Pfam; PF15608; PELOTA_1; 1.
DR   Pfam; PF15609; PRTase_2; 1.
DR   Pfam; PF11202; StiP; 1.
DR   Pfam; PF12500; TRSP; 1.
DR   SUPFAM; SSF53271; PRTase-like; 1.
PE   4: Predicted;
KW   Glycosyltransferase {ECO:0000313|EMBL:ATL27455.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000221011};
KW   Transferase {ECO:0000313|EMBL:ATL27455.1}.
FT   DOMAIN          35..222
FT                   /note="Orotate phosphoribosyltransferase-like"
FT                   /evidence="ECO:0000259|Pfam:PF15609"
FT   DOMAIN          269..406
FT                   /note="TRSP"
FT                   /evidence="ECO:0000259|Pfam:PF12500"
FT   DOMAIN          452..702
FT                   /note="Cysteine protease StiP N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11202"
FT   DOMAIN          729..808
FT                   /note="PELOTA RNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF15608"
SQ   SEQUENCE   826 AA;  88107 MW;  B21FC7BD1E34C244 CRC64;
     MRNMTYVTED AVWSGTWVAE RLGVGLEGDE GLRGLLGLAL RRNPKRAHLL VSNVLGKHVP
     QRPSVVHAAG HDLGVRVREL LGDVEARRAV VLGYAETATG LGHSVADGLG LAPYLHSTRR
     PVEGVERAGG FEESHSHATS HLLLPEDPGL LAGDGPLVLV DDEFSTGNTV LNTIRALHER
     FPRGRYVIVA LVDMRSPDDR GRLADFAREI GARVDLIATA SGTVRLPDGV LEKGQALVAE
     HESAAVPRPR GERAQVARVE LDWPREIPDG GRHGFTPAHR AALAAALPGM AARVADALDG
     GARRVLVLGF EELMYAPLAL GVELERRGGA EVRFSTTTRS PVLAVDDPGY AIRTRIAFPA
     HDDPADGPGT RYAYNVAGGG FDAIVAVVDS AADTPQLHAP DGLLAQLSAH TGQVLLAVIP
     SYVPSCAPSY DSSCAPERPT MLPEPLRGPT FSSYAPEDVG WLLQDLSDVT LEAPTEEREE
     AIQSGGAHYA ESLPVEYQPS AQYQDLFRAA LDTSAARIAR AVGTVTETVL AERSPRPVLV
     SLARAGTPVG VLMRRWAAHR HGLDLPHYAV SIVRGRGIDA NALRWLAAHH DPADVVFVDG
     WTGKGAITRE LADAVREFEE GGGPAGFSPE IAVLADPGSC VRTYGTREDF LIPSACLNST
     VSGLISRTVL RADLVGPDDF HGAKFYRELA DTDVSGDFVD TVAARFGEVA DAVDTQVKEV
     LAADRAPTWE GWAAVERISE ELGIHDVNLV KPGVGETTRV LLRRVPWKIL ARAGAGADLD
     HVRLLAEQRG VPVEEVAELP YTCVGLIHPK YTRGATGADG RAVAAK
//