ID A0A291QA76_9ACTN Unreviewed; 992 AA.
AC A0A291QA76;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=OmpR/PhoB-type domain-containing protein {ECO:0000259|PROSITE:PS51755};
GN ORFNames=KY5_3514 {ECO:0000313|EMBL:ATL28532.1};
OS Streptomyces formicae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1616117 {ECO:0000313|EMBL:ATL28532.1, ECO:0000313|Proteomes:UP000221011};
RN [1] {ECO:0000313|EMBL:ATL28532.1, ECO:0000313|Proteomes:UP000221011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KY5 {ECO:0000313|EMBL:ATL28532.1,
RC ECO:0000313|Proteomes:UP000221011};
RA Holmes N.A., Devine R., Qin Z., Seipke R.F., Wilkinson B., Hutchings M.I.;
RT "Complete Genome Sequence of Streptomyces formicae KY5, the formicamycin
RT producer.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; CP022685; ATL28532.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A291QA76; -.
DR KEGG; sfk:KY5_3514; -.
DR Proteomes; UP000221011; Chromosome.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 4.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000221011};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 25..121
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 862..895
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 25..121
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 992 AA; 106709 MW; BD07F6E11020AA5C CRC64;
MVDVPRVPEQ WRPASGNTPE ERTEGEFPEV QASRFSVLGP VRAWHGTEQL NTGSPMQRAL
LAALLLRDGR TATASELIDA LWGDEPPSQA LAAVRTYASR LRKVLPPGVL LSESGGYAVR
VTEGALDLTA AEDLWAAAEK ARGVGDLCQA RSLVNKALGL WDGEPLANVP GPYAETQRTR
LEEWRLQIVE SRLDMDLEQG CHAEAVSELT ALTAAHPLRE RLRELLMLAL YRSGRQAEAL
AVYADTRRLL ADELGVDPRT GLKELQQRIL QADPALSEPS AGDPEPATTV VRPAQLPATV
PDFTGRKSFV DELSDILSTA EGRVMAVSAL AGIGGVGKTT LAVHVAHVAR THFPDGQLYV
DLQGAGARAA EPETVLGAFL RALGTADSAI PESLEERAAL YRSVLDGRRV LVLLDNARDA
AQVRPLLPGM EGCAALVTSR VRMVDLAGAH LVDLDVMSPE EALLLFTRIV GDERVTSERE
AALDVVAACG FLPLAIRIAA SRLAARRTWT VSTLAAKLAD ERRRLDELQA GDLAVKATFE
LGYGQLEPAQ ARAFRLLGLA DGPDLSLAAA AAVLDLPLED TEDLLEALVD TSLIESAAPG
RYRYHDLVRL YARACAERDE QPPSERDAAM SRLLDFYLAS AARVYAIERP GDRTVSHLEV
THHLGLEFDD AATAFSWLRA EAACILACVQ QSLAPNSLRR AVDLILAAKN LAESGASSHR
YEAVTRAARD VAAATGDAYA EGRARVSLAQ VLNKLGRFHD AYAELELAVQ LALESGDPWT
HGNALNEQGI VNNCINQPAV GEGQLLQAIS AFRADGNRHS EASALCNLSR ALLAMGRTNK
SIELAQQGMA IYSELGVTFR LANAKYALGL ALSQAGRHSE ALDQLTDALE IFRDSRQRLW
QGTTHYRIAQ VSFSDRRVTQ AAQHAEQALS TGCVGGDWMR ANVLTILGRA LRALGQVDRA
QACWSEALAI HEAGGAPEAA QLRELLKPVA AA
//
