ID A0A291QF93_9ACTN Unreviewed; 512 AA.
AC A0A291QF93;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Ricin B lectin domain-containing protein {ECO:0000259|SMART:SM00458};
GN ORFNames=KY5_5169 {ECO:0000313|EMBL:ATL30187.1};
OS Streptomyces formicae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1616117 {ECO:0000313|EMBL:ATL30187.1, ECO:0000313|Proteomes:UP000221011};
RN [1] {ECO:0000313|EMBL:ATL30187.1, ECO:0000313|Proteomes:UP000221011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KY5 {ECO:0000313|EMBL:ATL30187.1,
RC ECO:0000313|Proteomes:UP000221011};
RA Holmes N.A., Devine R., Qin Z., Seipke R.F., Wilkinson B., Hutchings M.I.;
RT "Complete Genome Sequence of Streptomyces formicae KY5, the formicamycin
RT producer.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP022685; ATL30187.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A291QF93; -.
DR KEGG; sfk:KY5_5169; -.
DR Proteomes; UP000221011; Chromosome.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR CDD; cd00161; RICIN; 1.
DR CDD; cd01823; SEST_like; 1.
DR Gene3D; 2.80.10.50; -; 2.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR InterPro; IPR037460; SEST-like.
DR InterPro; IPR013830; SGNH_hydro.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR PANTHER; PTHR37981; LIPASE 2; 1.
DR PANTHER; PTHR37981:SF1; SGNH_HYDRO DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13472; Lipase_GDSL_2; 1.
DR Pfam; PF00652; Ricin_B_lectin; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637460-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000221011};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..512
FT /note="Ricin B lectin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012810063"
FT DOMAIN 387..511
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
FT ACT_SITE 87
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT ACT_SITE 343
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT DISULFID 108..131
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT DISULFID 188..199
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
SQ SEQUENCE 512 AA; 54631 MW; 7FBA0C22F3FD6827 CRC64;
MKRIRRSGRG RLRGSFAAAV AMAAVLGTAA AVPAQAADGG AAKAPASTPL PPELEKIRAD
EATKLYGSPG ERPMADRKTG LISLGDSEIS GEGVGTYEPG TDGPDNWCHR SPDAAIHRTG
IPADVTYNVA CSGAQTVNIK IGGQKQYADE LVQSDNLAIK ARNTKIKTIL LVIGANDDLN
FSGVMTDCVT RFLLSQGACA GKYNDGWQAR VDGLVPKVEQ SIRDLKTVMK DAGYQAGDYK
LVAMGYPSPI GPDFRDNPTF PGKLVCGGLG YDSDTEWGRN YAVPTFATGM RKAAKNAGAT
YLDNSRLFQG HEVCMEDTWA RGLYIDVSNP FPPDSNSVRQ SFHPNARGHA AFASCLTQIY
NSGYGEGSCA DPASTGSPKL YKGAWDDAYK PLKNEGTGTC VDVDASKSRN GTKVQGWDCT
GNRNQTWWYD DTQKSLHTGL TQDRCVDVPE GSYKEGTAVT LWNCHGGDNQ KFVRQSGTVR
PAAEGGLCLT LAGAKEPVRL QKCTGAANQR FA
//
