ID A0A292YC27_9BACL Unreviewed; 767 AA.
AC A0A292YC27;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Pyruvate synthase {ECO:0000313|EMBL:GAX88702.1};
GN ORFNames=EFBL_0314 {ECO:0000313|EMBL:GAX88702.1};
OS Effusibacillus lacus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC Effusibacillus.
OX NCBI_TaxID=1348429 {ECO:0000313|EMBL:GAX88702.1, ECO:0000313|Proteomes:UP000217785};
RN [1] {ECO:0000313|Proteomes:UP000217785}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=skLN1 {ECO:0000313|Proteomes:UP000217785};
RA Watanabe M., Kojima H., Fukui M.;
RT "Draft genome sequence of Effusibacillus lacus strain skLN1.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAX88702.1}.
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DR EMBL; BDUF01000007; GAX88702.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A292YC27; -.
DR OrthoDB; 9794954at2; -.
DR Proteomes; UP000217785; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 3.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR PANTHER; PTHR32154:SF0; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Pyruvate {ECO:0000313|EMBL:GAX88702.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000217785};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 36..261
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 284..387
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
FT DOMAIN 549..656
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 767 AA; 84982 MW; 4DC66CD451B92360 CRC64;
MALKETDLQE KTIPKTDVDI EQKTDFRSGN EMAAQAAAQI NYHVMGYFPI TPSTEIAEYL
DEMKTEGKHD IVLIPADGEH GSAGICYGAA TAGGRVFNAT SANGFLYMIE QLPVQSGTRF
PMVMNLVTRS VSGPLDIRGD HSDLYFGLNI GWPILLAKDP QAVYDMNLIA LRVAEHKDVR
LPVIVAYDGF FTSHQKRRVQ YFSNRDAVQK FVGETPKGYV DSLDTSNPVT IGPYMNDPDY
INNKYQQSEA MYNAERVYLE VAEEYAKISG RKYGLLDLYM MEDAEVAVFL LNSASDTAKD
VVDKLRKQGI KAGVIAPEII RPFPKKAIQE ALKNVKVVLV GERADSFGGH GANLTHEVKA
ALQEIKADTT VLSRIYGLGG KDFYADDAEA FFQLCLDVLQ GKEVKAFDYF GHTPGKAELV
PQRVLKPLTK EETTGFVSVT KDEETGELKV KMPPLRGLTA KAKRIAPGHG ACPGCGIFPG
LETFYKGIEG DVVVLFHTGC AMVVTTGYPY SSHRITYIHN LFQNGAATLS GVVEMFWERK
RRGEILVSDD ITFIMITGDG GMDIGMGPAI GAALRNHKMI ILEYDNEGYM NTGAQLSYST
PLGHMTATSN VGGFQSGKPF HHKDTAQIMA ATNIPYVFTG TEAFPQDLIK KAAKAQWYAK
NEGMAYGKIL ISCPLNWKAA DEAGNAIVAN AVNTCFFPLY EVEHGITKIT YDPEEKGKRQ
PVSEWLKMLG KTKHLLKPEN AHYLKMFEDE VERRWRRLKA KHENPYL
//
