ID   A0A292YY95_9PSEU        Unreviewed;      1121 AA.
AC   A0A292YY95;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Vancomycin B-type resistance protein VanW {ECO:0000313|EMBL:GAY11090.1};
GN   ORFNames=TOK_5576 {ECO:0000313|EMBL:GAY11090.1};
OS   Pseudonocardia sp. N23.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Pseudonocardia.
OX   NCBI_TaxID=1987376 {ECO:0000313|EMBL:GAY11090.1, ECO:0000313|Proteomes:UP000222857};
RN   [1] {ECO:0000313|EMBL:GAY11090.1, ECO:0000313|Proteomes:UP000222857}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N23 {ECO:0000313|EMBL:GAY11090.1,
RC   ECO:0000313|Proteomes:UP000222857};
RA   Yamamoto N., Saito Y., Inoue D., Sei K., Ike M.;
RT   "Characterization of newly isolated Pseudonocardia sp. N23 with high 1,4-
RT   dioxane-degrading ability.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAY11090.1}.
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DR   EMBL; BEGX01000069; GAY11090.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A292YY95; -.
DR   Proteomes; UP000222857; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007391; Vancomycin_resist_VanW.
DR   InterPro; IPR022029; YoaR-like_PG-bd.
DR   PANTHER; PTHR35788; EXPORTED PROTEIN-RELATED; 1.
DR   PANTHER; PTHR35788:SF1; EXPORTED PROTEIN-RELATED; 1.
DR   Pfam; PF12229; PG_binding_4; 1.
DR   Pfam; PF04294; VanW; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        572..592
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          774..879
FT                   /note="YoaR-like putative peptidoglycan binding"
FT                   /evidence="ECO:0000259|Pfam:PF12229"
FT   REGION          1..364
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          387..470
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          492..567
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          832..856
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        227..248
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        253..273
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        310..341
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        506..524
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1121 AA;  112811 MW;  F583CE0C78DC7ED7 CRC64;
     MRGEEGKSDV MTEREPGVDE GDGNRTVDEQ AAAAAGSPVD AAPGTDTAGT EAARQSSSLS
     GDDLFAVARP SDTTGPPSAP AASSVPPSAE PASDAVRSEA PPSDRLVPGA PVSDAPAAAT
     AAGSPVVAMK PGASTASPSP SFAADGSALS GSAAPVSPAA PVSPAAPVSP AAPVSPVDAG
     EGPVDAGADP GDAEVRAARS ESAAAWAGAD NSGVDASGAD VSGADVSRAD VSRDEVRGAD
     DVRTVDRPAD PSPELGAPAP DEAEPPRPAD APQKDPSADP ARPVAEPART EPVAEPARSE
     PVAEPARSEP TVEPARRELS GPEPADRAVA EPADRAVAEP ADRPVAEPAG RPAAEAPAVS
     AAAPTVAPRN WFAEPDAEAT AVLPAVRPGS TQADPAHGTG AQVDPARAAE SHGPTASPVD
     PATVRIPARR TEQQVERPTE VIPAVTADAA DGARRGTDRR PDHAGAPTIL TKVPSAAAAA
     GGATAVLGAA AATRSGADAG RTTTAIRAGG TGSGTGTSAG SSGAGRTGPG DPGPGSDATR
     PVPPEGDSGS DGPDGPDTPG GGSKGRRRRR PLLVAAAVVG LLAVLYVVDL LLGMGDMPRG
     VSVAGQAVGG MSRQEAEASL RATIDPRATQ PVVVTAGDVR TEIDAATAKL GVDWGATIER
     AGAQPVNPIA RIESFFVDKD FDVVSTADER AVTAALEGMG PLVDDEATEA SVRFDGLEPV
     PVMPEDGHRL DVPAAVPLVA TKWATGTPVE LPLATLKPIT TADDVRQAVD SIARPAVSAP
     ITVTGEGAQG TLDPADIAKA LTFRADAGAT PRLVPELNPE IVSDALSPQL EKTEKPGRDA
     TLDVSGPTPV VVPSQDGRGI DYPATLTTMV PVLKAQAPRQ VAAVYGDKPA KVTTEDIEKL
     GIAGEISTFT TGGFAADSGR NIKRAAEQID GTIVKPGETF SLNALTNPRN AANGYVEAGI
     IEDGHPARGI GGGVSQVATT VYNAAYFAGM VDVAHKEHSF YISRYPAARE ATVFDNVIDL
     KFRNDGPTGV LIKTFWTPSS LTVKIYGTKR YEVTSTTGPR TNETPPSPVT IPAGQPCSAS
     SGAPGFTASD TRTLRNVQTG EVRTEKRTVR YNPSPIVVCG G
//