ID   A0A292Z3C0_9PSEU        Unreviewed;       405 AA.
AC   A0A292Z3C0;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Threonine dehydrogenase and related Zn-dependent dehydrogenases {ECO:0000313|EMBL:GAY12980.1};
GN   ORFNames=TOK_1533 {ECO:0000313|EMBL:GAY12980.1};
OS   Pseudonocardia sp. N23.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Pseudonocardia.
OX   NCBI_TaxID=1987376 {ECO:0000313|EMBL:GAY12980.1, ECO:0000313|Proteomes:UP000222857};
RN   [1] {ECO:0000313|EMBL:GAY12980.1, ECO:0000313|Proteomes:UP000222857}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N23 {ECO:0000313|EMBL:GAY12980.1,
RC   ECO:0000313|Proteomes:UP000222857};
RA   Yamamoto N., Saito Y., Inoue D., Sei K., Ike M.;
RT   "Characterization of newly isolated Pseudonocardia sp. N23 with high 1,4-
RT   dioxane-degrading ability.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAY12980.1}.
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DR   EMBL; BEGX01000137; GAY12980.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A292Z3C0; -.
DR   OrthoDB; 241504at2; -.
DR   Proteomes; UP000222857; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd08282; PFDH_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR014184; HCHO_DH_non_GSH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   NCBIfam; TIGR02819; fdhA_non_GSH; 1.
DR   PANTHER; PTHR42813:SF3; GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          44..153
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          206..272
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   405 AA;  41974 MW;  C9B4964301BC6CD3 CRC64;
     MSGNRAVAYV GPGEVEVHDI PYPTLELQDG PGVNPANVGR KCNHGVILKV VTTNICGSDQ
     HMVRGRTTAP EGLVLGHEIL GEVVEVGSDV EFTKVGDLAS VPFNIACGRC RNCKEGKTGI
     CLNVNPDRPG SAYGYVDMGG WVGGQAEYVM VPYADFNLLV FPDRDQAMEK VRDLTMLSDI
     FPTGFHGAVT AGVKPGATVY VAGAGPVGLA AAAGAQLLGA AVVIVGDLQE ERLAQARTFG
     CETIDVSKGD PKDQIEQLLG VPEVDAGIDA VGFEARGHGE GSGTEAPATV LNSLMEITAA
     GGALGIPGLY VTGDPGGIDD AAKVGSLSLS LGTGWAKSLS FTTGQCPVMR YNRGLMMAIL
     HGRVQIADAV NATVISLDDA PRGYQEFDKG APRKYVIDPH GTLAA
//