ID A0A2A1ZN43_9BACT Unreviewed; 425 AA.
AC A0A2A1ZN43;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Cation/H+ exchanger domain-containing protein {ECO:0000259|Pfam:PF00999};
GN ORFNames=CI105_06420 {ECO:0000313|EMBL:PAT01514.1};
OS Candidatus Izimaplasma bacterium ZiA1.
OC Bacteria; Mycoplasmatota; Candidatus Izimaplasma.
OX NCBI_TaxID=2024899 {ECO:0000313|EMBL:PAT01514.1, ECO:0000313|Proteomes:UP000217826};
RN [1] {ECO:0000313|EMBL:PAT01514.1, ECO:0000313|Proteomes:UP000217826}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZiA1 {ECO:0000313|EMBL:PAT01514.1,
RC ECO:0000313|Proteomes:UP000217826};
RA Kim S.-J., Rhee S.-K.;
RT "Direct submision.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAT01514.1}.
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DR EMBL; NQYJ01000007; PAT01514.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A1ZN43; -.
DR OrthoDB; 9778229at2; -.
DR Proteomes; UP000217826; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR43021; NA(+)/H(+) ANTIPORTER-RELATED; 1.
DR PANTHER; PTHR43021:SF2; NA_H_EXCHANGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000217826};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 13..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..412
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 425 AA; 45446 MW; 18FAEFC35716CED8 CRC64;
MTDLLNILSS SNVANYEALL VMGTIVVVGM FVGKLFERIK IPNITGYIFA GLILGFVLFQ
IGLDDIVHML EIVSSVALGF IAYGIGRELI FSKLRKSGKE VIVITIMQAV FTTAIVSLGL
ILFKVPVAVA LIFGAIATAT EPASIMLLTK RMKTKGPLTD TLIPLVGLDD AVGIVIFGIL
LSVGKSLNSG AELHISEIIL DPALEVIFSI LIGVAIGLFC GFIIKSVKAR NDDKYETFLN
VSIFGVFAAV AISKIGFNIG DLQIHLSPIL TPMVLGVTVA NIVSRVRSHE MDLAVDKFTP
PILIAFFTLA GAELISAFLN QSNIAYGAMI TTIVLYITLR IVGKISGAWV GAKMMHSVDS
VRKYLGISLL PQAGVALGMA YQARTDFAEH GVTILIVILV ATLFYALIGP IGVKYSLIKA
KETNV
//
