ID A0A2A2A031_9CORY Unreviewed; 674 AA.
AC A0A2A2A031;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=CKJ84_09240 {ECO:0000313|EMBL:PAT14481.1};
OS Corynebacterium sp. NML 120412.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=2029401 {ECO:0000313|EMBL:PAT14481.1, ECO:0000313|Proteomes:UP000218861};
RN [1] {ECO:0000313|EMBL:PAT14481.1, ECO:0000313|Proteomes:UP000218861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NML 120412 {ECO:0000313|EMBL:PAT14481.1,
RC ECO:0000313|Proteomes:UP000218861};
RA Bernier A.-M., Burdz T., Bernard K.;
RT "Whole genome sequences of 6 clinical strains closest to Corynebacterium
RT imitans.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAT14481.1}.
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DR EMBL; NSGL01000003; PAT14481.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2A031; -.
DR Proteomes; UP000218861; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..674
FT /note="VWFA domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012245805"
FT TRANSMEM 643..666
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 71..256
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 34..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 581..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..610
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 674 AA; 72630 MW; 8E575960E5B6CD26 CRC64;
MSHVREKSRA VAVLILAAAC VLIWVAPAFA TETATSTNRP VESSTAVSTE TRTLSSSTVR
ASASEGSADA KAALILDSSF SMLEEDADGP RIDAAKKATH ELIDSLPDTA QMGFFAYGAQ
ESNAPDNREK GCRDIQRLVP IGEVDKQEFS SAIDGLTPKG YTPMGNALRE AAEELGDEGE
RSIILVSDGI DTCAPPEVCD VAKELAGQGV DLTIHTVGFK ADEEARAELE CIAEAGGGQF
LEAADASSLA QSLKFLAQRG VENYETGGTE FEFSDTPEGA KWLGEGQYQT TVTPDRGTAK
DRYFRISVPP RHHARMVFTP VWQTDGMWEG GHLKIEPVEV TNEGDEECGW FPGKRTAFVS
SGPDYGIDSA TVSAERNGES DMECDMSDIL VKTQISDVTG VDTGDIGLEV SVFYEPIPSD
EEKTEWSDGK IIKAGDYLGE MPMKNPEPIS GGTGFNNAVE ITEGAYSDNI VPGEFRFFKI
PVAYGQRPVV KVKTPESVAH NADSLGFGIY DPMRNELVRT PLHFFMGAAE SDAETLSQYV
WHGTHTPYHG EYYIWVGMGW VHEGYDIAGV EQPFEFEVVI DGEPGNGGPD WTPTHEDGPE
PSDEPIKFDA ADSTAETSAS QEESDGDEEV NAASDEQDGG FGLVPTLLGG LLVLLLIAAA
VVFVIVRKQR GNWQ
//
