ID A0A2A2AL12_9BURK Unreviewed; 1419 AA.
AC A0A2A2AL12;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=ATP-dependent RNA helicase HrpA {ECO:0000313|EMBL:PAT38467.1};
GN Name=hrpA {ECO:0000313|EMBL:PAT38467.1};
GN ORFNames=CK625_02990 {ECO:0000313|EMBL:PAT38467.1};
OS Vandammella animalimorsus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Vandammella.
OX NCBI_TaxID=2029117 {ECO:0000313|EMBL:PAT38467.1, ECO:0000313|Proteomes:UP000218054};
RN [1] {ECO:0000313|EMBL:PAT38467.1, ECO:0000313|Proteomes:UP000218054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NML00-0135 {ECO:0000313|EMBL:PAT38467.1,
RC ECO:0000313|Proteomes:UP000218054};
RA Bernier A.-M., Bernard K.;
RT "WGS of Clinical strains of the CDC Group NO-1 linked to zoonotic
RT infections in humans.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAT38467.1}.
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DR EMBL; NSJB01000001; PAT38467.1; -; Genomic_DNA.
DR Proteomes; UP000218054; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:PAT38467.1};
KW Hydrolase {ECO:0000313|EMBL:PAT38467.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000218054}.
FT DOMAIN 57..231
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 255..432
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 599..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1074..1144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1082..1100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1116..1138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1419 AA; 157009 MW; 7F6C6B550B16EDAF CRC64;
MNSASDSATD AASGPAAAPP AAPHASAAPA VPNAPPAPLH ISFPDSLPVS VRRHEIERAL
RAHQVVIVCG ETGSGKTTQL PKIALALGRG LGRGQRGKDG RRGQWIGHTQ PRRIAASSVA
KRIAEELQTP LGEVVGYKVR FNDRLGPNAR VKLMTDGILL AETQTDPLLK AYDTLIIDEA
HERSLNIDFL LGYLKQILPR RPDLKLIITS ATIDAERFAQ HFASAKGPAP VLYVSGRTYP
VEIRWRPFEE SRETDLNTAI ADAVDELWQG RPGGDILVFL PGEREIREAA DHVHKHLSHD
PVRRHCTVLP LFARLSQAEQ DRVFETGGPP RVVLATNVAE TSLTVPGVRY VIDTGTARVK
RYSYRSKVEQ LLVEPISQAA ANQRSGRSGR VADGVAIRLY EEADFAARAR FTDPEILRSS
LAGVILRMKS LGLGAVEEFP FLEAPSQRAI TDGYQLLQEL GAVDEQRELT EMGRQMARLP
LDPRVARMLI EARARGALQE VLVVAAALSV QDVRDRPLDK QAQADQAHAR FDDEKSEFTS
YLKLWQWIHD ARGGKAASLP SARQQAQAVA QAQGRGKAGR GHAALPVAQR AVAAPASPAA
ATAPAVPGPG PEGAAPAQAT HRLSNRQYEN LLRSHYINVR RVREWRDIHQ QLAAAVAEQG
WKLHEQNGPA SYEALHLSLL AGLLGNVGFK PDEAEHYLGA RGIKFYRHPG ARLRKKPGRW
VVAAELVETT RLYGRGMANI EPQWLEEVGA HLLKKQLLEP HWEQKAGEAV ALERATLYGL
LVYSGRRVPF ARIDPAAARE IMIRQALVQG DYASEWERKF PFLATNRKRI AKVEELEHKS
RRQDVLVDEE LIYAFYDRLI PEAVCNGRQL EQWYRQERRQ QPQLLELQKD ELMRHEAAGI
TTAAFPPTIK LAGMDLNASY LHEPGNPRDG VTVTIPLYAL NQVQEARADW LVPGMLGAKV
QALLKSLPQR PRSRLLPLAE TAGAIAKAWL EEGSFAQGDL HERLRQWVRA KTGLEIKPTD
FKADMLSAHL FMNFRVVDEH GRQLGQGRNL AALKAELGQQ ARGAFQALAG LKLAQSEEGG
KSSGEKTGEI TAEKAGKDAG KNARAAAAAT PTPASAAGQG KGQTPAAQSE SNALGEPEQR
HTSWDFGELP EIMEWGKGSR KLIGFPALVD QGDAVTIEVF DEPEAAAQVH RQGLARLFAL
HIKDALKYLE KNIPELQKMA VAYMLLGTLE ELRAQIIAVA IELAFLQEPL PINAEQFEQR
LKDGRPRLSL LAQEVARLAG QILAEYAQIV RKLKDMKGAE QAVADVRQQL ERLMGKRFVQ
ATPQAQLKHY PRYLKAMLMR LDKYREDPAR DQARQGEIAP LEARYWKLLA QRKGQQDAAL
QDYRWLLEEL RVSFFAQQLR TPQPVSVKRL EKVWAQVVA
//
