ID A0A2A2EI49_9BIFI Unreviewed; 368 AA.
AC A0A2A2EI49;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:PAU68849.1};
GN ORFNames=B1400_1233 {ECO:0000313|EMBL:PAU68849.1};
OS Bifidobacterium italicum.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=1960968 {ECO:0000313|EMBL:PAU68849.1, ECO:0000313|Proteomes:UP000217986};
RN [1] {ECO:0000313|EMBL:PAU68849.1, ECO:0000313|Proteomes:UP000217986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=70 {ECO:0000313|EMBL:PAU68849.1,
RC ECO:0000313|Proteomes:UP000217986};
RX PubMed=28837128; DOI=10.1038/ismej.2017.138;
RA Milani C., Mangifesta M., Mancabelli L., Lugli G.A., James K., Duranti S.,
RA Turroni F., Ferrario C., Ossiprandi M.C., van Sinderen D., Ventura M.;
RT "Unveiling bifidobacterial biogeography across the mammalian branch of the
RT tree of life.";
RL ISME J. 11:2834-2847(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAU68849.1}.
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DR EMBL; MVOG01000026; PAU68849.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2EI49; -.
DR Proteomes; UP000217986; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 34..319
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 368 AA; 39699 MW; 7D011A893189D8D6 CRC64;
MVEEVAGSVE AADATIEATA TMPVIGPEGI DCPRHIAIVG LGLIGGSLAL RLRSAGVRVS
AWNHRPHPYA AARAAGIDCK DGLEELVAEH PDVIVLCNPL VAMPGILETI KPIIDPARTT
LTDVGSVKGL VREQVHAAGI TDCYVGAHPM TGNEHSGWSA ADPSIFDNAL WALTYDHHTE
YARIVQVAGM ITRGLRNTMI VIDDETHDRA ASLISHMPHV VSTALINELT ANPDRNIAAA
LSAGSWRDMT RVALTDPERT AAMVVENAGN VEELLRTMAQ RLQSIADALR DGDPTAIRGF
FTEGQPYRDY KAKQGAAFET GETQTVFTTL KVSADDWRRD LLDSAKRGEH IVRFTSGHHA
LAERQFTI
//
