ID A0A2A2ELC5_9BIFI Unreviewed; 374 AA.
AC A0A2A2ELC5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Sortase {ECO:0000313|EMBL:PAU69871.1};
GN ORFNames=B1400_0406 {ECO:0000313|EMBL:PAU69871.1};
OS Bifidobacterium italicum.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=1960968 {ECO:0000313|EMBL:PAU69871.1, ECO:0000313|Proteomes:UP000217986};
RN [1] {ECO:0000313|EMBL:PAU69871.1, ECO:0000313|Proteomes:UP000217986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=70 {ECO:0000313|EMBL:PAU69871.1,
RC ECO:0000313|Proteomes:UP000217986};
RX PubMed=28837128; DOI=10.1038/ismej.2017.138;
RA Milani C., Mangifesta M., Mancabelli L., Lugli G.A., James K., Duranti S.,
RA Turroni F., Ferrario C., Ossiprandi M.C., van Sinderen D., Ventura M.;
RT "Unveiling bifidobacterial biogeography across the mammalian branch of the
RT tree of life.";
RL ISME J. 11:2834-2847(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAU69871.1}.
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DR EMBL; MVOG01000005; PAU69871.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2ELC5; -.
DR Proteomes; UP000217986; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd05830; Sortase_E; 1.
DR Gene3D; 2.40.260.10; Sortase; 1.
DR InterPro; IPR005754; Sortase.
DR InterPro; IPR023365; Sortase_dom-sf.
DR InterPro; IPR042003; Sortase_E.
DR NCBIfam; NF033747; class_E_sortase; 1.
DR Pfam; PF04203; Sortase; 1.
DR SUPFAM; SSF63817; Sortase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT ACT_SITE 153
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT ACT_SITE 221
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ SEQUENCE 374 AA; 41672 MW; 50C0096F1ADBCF5E CRC64;
MKNGGENTTM AHSQHAAPRR TRSVGRSIVT IIAELLLTFA AICGLYVAWM QWWTGVQSDH
VQQETRAQVA WAQPNDGGTL TIAQPQEGEP PVQPQEALVG ELIARVYIPR FGDQWERNLV
QGTELAELNQ HGLGHYVDSQ MAGQVGNFAI AGHRNGYGQP LGDVDKLEKG DAIVIRSKDY
WYVYHYTDYT IVTPDEGWVI GANPEHPGEP PTKRLITMTT CEPKYTTPTH RWVSFGEFAY
WAKVADGIPK ELAKTDSNGA VEFINNERHS FASSITSLAP WVWGALVVYL VVFLAAAVAW
RWPALRAIRE GDRPLPDADI YGWLLRHQPG VAPIRWLLML LLVFAAAAAL FQWGFPWAAA
NVPFLQQMSN YVAV
//
