ID A0A2A2GE49_9BACT Unreviewed; 816 AA.
AC A0A2A2GE49;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:PAU95264.1};
GN ORFNames=CK503_03445 {ECO:0000313|EMBL:PAU95264.1};
OS Aliifodinibius salipaludis.
OC Bacteria; Balneolota; Balneolia; Balneolales; Balneolaceae; Fodinibius.
OX NCBI_TaxID=2032627 {ECO:0000313|EMBL:PAU95264.1, ECO:0000313|Proteomes:UP000218831};
RN [1] {ECO:0000313|EMBL:PAU95264.1, ECO:0000313|Proteomes:UP000218831}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WN023 {ECO:0000313|EMBL:PAU95264.1,
RC ECO:0000313|Proteomes:UP000218831};
RA Liu D., Zhang G.;
RT "Aliifodinibius alkalisoli sp. nov., isolated from saline alkaline soil.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAU95264.1}.
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DR EMBL; NSKE01000002; PAU95264.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2GE49; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000218831; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000218831};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 512..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 571..773
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 816 AA; 92146 MW; 269E5A539883737C CRC64;
MAVRFSLLSG HTNVSIHQTY QFPFASYPAI RITLLLAAGI IVDYQADLSL SVWTLIFGFA
AIFYLIAEVT YRKSLDSRTY NIAILSYLGL ILSFGGTWHS FWDYRDLPEE AQVINTYTWE
ELTFSGNIHQ IKQTSTGKFQ VDVDVETTIF PDDLVWDKSF TLRAVLNPAY HNVPVDLELG
NKITFVATVY PLEEKRNPSE FNYKQYLASQ NIHAQVGIQQ ITSITPVHTN WRWTFLRKHV
LNAIDNNFSK ESSSLAKALL IGYKNELARE DKISFSRAGL SHIMAVSGLH VGFLLFPFWL
VIPFFWTLKY GKQIGITLLI ITLFIYAGLT DFSPSVTRAS LVGILLAYGK LFHKVRDSKN
LTAVAALIIL LINPSDLFSI GFQLSFGAVY IILLTAPVIQ RRLPAWIRFS WYGKPIMIII
ISFIVQVGLF PLLAYYFGEF SLVGPLANAF VIPFLGIVVP FALAVLLITP FASDVAQTLN
YPVDIFLQWL HNFVDFAANL PWSWVQVHVD SLLFFGIWIV IIFFIASLPI PKLRWKFLAL
LLLVSCLHQG NRVVHKLSPT TLNLTFFDVG QGDAALISTP NNKHFLIDVG RWQPDYNSAK
YIIIPHLKEQ GIEKLDAVFL SHPHADHIGG ILEIIDSFPV DTIYNSGTSY NSQLYKTYNR
KASEHKIPIK SLHAGDQINI DPAIRMFVYG PQKSVAQSNV NNRSLVLELI YGDTEFLFMG
DAEHRQEKNI LKHFPGLINT DFLKVGHHGS KTSSGTLLLQ STTPHIGVVS LAKSNRFGHP
HREASRRIHE YISSLYFTSL EGAVQFSSDG KNIYKQ
//
