ID   A0A2A2GSA6_9HELI        Unreviewed;       400 AA.
AC   A0A2A2GSA6;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Phosphonopyruvate decarboxylase {ECO:0000313|EMBL:PAU99909.1};
GN   ORFNames=B9T66_05560 {ECO:0000313|EMBL:PAU99909.1};
OS   Helicobacter sp. TUL.
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=1848928 {ECO:0000313|EMBL:PAU99909.1, ECO:0000313|Proteomes:UP000218502};
RN   [1] {ECO:0000313|EMBL:PAU99909.1, ECO:0000313|Proteomes:UP000218502}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TUL {ECO:0000313|EMBL:PAU99909.1,
RC   ECO:0000313|Proteomes:UP000218502};
RA   Van Der Mee-Marquet N., Benejat L., Diene S.M., Gaia N., Cherkaoui A.,
RA   Lemaignen A., Ducournau A., Lacomme S., Gontier E., Bernard L., Megraud F.,
RA   Goudeau A., Lehours P., Francois P.;
RT   "Helicobacter caesarodunum: a novel human pathogen identified in a
RT   bloodstream infection.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAU99909.1}.
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DR   EMBL; NESU01000009; PAU99909.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2GSA6; -.
DR   Proteomes; UP000218502; Unassembled WGS sequence.
DR   GO; GO:0033980; F:phosphonopyruvate decarboxylase activity; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0032923; P:organic phosphonate biosynthetic process; IEA:InterPro.
DR   CDD; cd07035; TPP_PYR_POX_like; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   InterPro; IPR017684; Phosphono-pyrv_decarboxylase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR   NCBIfam; TIGR03297; Ppyr-DeCO2ase; 1.
DR   PANTHER; PTHR42818:SF1; SULFOPYRUVATE DECARBOXYLASE; 1.
DR   PANTHER; PTHR42818; SULFOPYRUVATE DECARBOXYLASE SUBUNIT ALPHA; 1.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE   4: Predicted;
KW   Pyruvate {ECO:0000313|EMBL:PAU99909.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218502}.
FT   DOMAIN          250..364
FT                   /note="Thiamine pyrophosphate enzyme TPP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02775"
SQ   SEQUENCE   400 AA;  44099 MW;  0235575F839559F7 CRC64;
     MLDVYAFGEI LEECGFRDFS GVPCSYLSPL INYAINKRRF IMANNEGEAI AIASGITLAS
     LESNMVLDDF SDRRNTFGVV LMQNSGLSNA LSPLTSLNYP FSIPILGFVS LRGERDESGN
     NTDEPQHELL GVITDKLLHT CEIEYMFLHA ELSQARTQIH KALEILQTGK SCFFIVRDKT
     FAKIALEVNP IQDLCIDKNT QSHEALPSRI QALEVIQRIA MDSQSVLLAT TGKCGRELYE
     LGDRENQLYM VGSMGCVGAL GLGIALKSHK KVMAVDGDSA LLMRLGSLST NAYYAKVRDA
     GNFCHILLDN QSHDSTGGQF NLSPFVDFCA IARACGYEVS RSVNTCTELN EVLDEFVHCK
     SGGAWFIYLR IAKGSKEPLG RPKITPKEVA IRLQNFLAKV
//