ID A0A2A2GSD7_9HELI Unreviewed; 862 AA.
AC A0A2A2GSD7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Chaperone protein ClpB {ECO:0000256|ARBA:ARBA00017574};
GN ORFNames=B9T66_05345 {ECO:0000313|EMBL:PAU99867.1};
OS Helicobacter sp. TUL.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1848928 {ECO:0000313|EMBL:PAU99867.1, ECO:0000313|Proteomes:UP000218502};
RN [1] {ECO:0000313|EMBL:PAU99867.1, ECO:0000313|Proteomes:UP000218502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TUL {ECO:0000313|EMBL:PAU99867.1,
RC ECO:0000313|Proteomes:UP000218502};
RA Van Der Mee-Marquet N., Benejat L., Diene S.M., Gaia N., Cherkaoui A.,
RA Lemaignen A., Ducournau A., Lacomme S., Gontier E., Bernard L., Megraud F.,
RA Goudeau A., Lehours P., Francois P.;
RT "Helicobacter caesarodunum: a novel human pathogen identified in a
RT bloodstream infection.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homohexamer. The oligomerization is ATP-dependent.
CC {ECO:0000256|ARBA:ARBA00026057}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAU99867.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NESU01000009; PAU99867.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2GSD7; -.
DR Proteomes; UP000218502; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000218502};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 4..146
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT COILED 411..491
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 862 AA; 96179 MW; 135E8CEAEA98B481 CRC64;
MNIFEKLTNQ LKETLDSAAA LALHSQNQEI NMAHMFWALL TNTQSVLNQA LNKLNIDKAP
IELEARSVAD KLPKSSSVTK ENLSISKNLS DALAKAQGEA TRNGDSYIAV DNFIIANLTD
SAYKEIFGKY LDSSELKKTL ESIRAGTKIT DQNDDSNFES LEKYGIDLTQ KALENAIDPV
IGRDEEITAM MQILIRKTKN NPILLGEPGV GKTAAVEGLA QRIVAKSVPL SLQNKRVIAL
DMSALIAGAK YRGEFEERLK AVINEVKKAG NIILFIDEIH TIVGAGASEG SMDAANILKP
ALARGELHTI GATTLKEYRK YFEKDAALTR RFQPITLNEP NTNEALQILR GIKQKLEAHH
NVSITDSALV AAAKLSQRYI PDRFLPDKAI DLIDEGAAEL KMQIESEPYE LSKIKRQIQS
LEVEKQALNM EKDKNNATRL EEIEQDLANY NEERRTLEGQ FENEKEVFRQ IAELKTQLDS
LQSQSEIAKR NGDYNKAAEI DYGKIPQIQE EEKKLQEKWD TMLKQGTLLK NAVTEEIIAG
IVSRWTQIPI KKMLQSQKER ILGIEDELAK SVVGQAEAIH AIARAIKRNK AGLSAPNRPI
GSFLFLGPTG VGKTQSAKSL ANFLFDSPKN LVRIDMSEYM EKHSVSRLVG AAPGYVGYEE
GGQLTEAIRR KPYSVVLFDE IEKAHPDVFN ILLQVLDDGR LTDNKGVVVD FSNTIIILTS
NIGSDKILEL HDKSDRENTV RDLLKGYFKP EFLNRLDDVV IFNPLELKDI MGIVDIMFEQ
IAQVAGQKGI QISLSDEAKA FIANAGFDPI YGARPLKRAL YEEIEDKLAE LILEDKLKEG
SKVQFVLEKD SDNHEYIQAI YS
//
