ID A0A2A2GUN3_9HELI Unreviewed; 531 AA.
AC A0A2A2GUN3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Flagellin {ECO:0000256|RuleBase:RU362073};
GN ORFNames=B9T66_01835 {ECO:0000313|EMBL:PAV00738.1};
OS Helicobacter sp. TUL.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1848928 {ECO:0000313|EMBL:PAV00738.1, ECO:0000313|Proteomes:UP000218502};
RN [1] {ECO:0000313|EMBL:PAV00738.1, ECO:0000313|Proteomes:UP000218502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TUL {ECO:0000313|EMBL:PAV00738.1,
RC ECO:0000313|Proteomes:UP000218502};
RA Van Der Mee-Marquet N., Benejat L., Diene S.M., Gaia N., Cherkaoui A.,
RA Lemaignen A., Ducournau A., Lacomme S., Gontier E., Bernard L., Megraud F.,
RA Goudeau A., Lehours P., Francois P.;
RT "Helicobacter caesarodunum: a novel human pathogen identified in a
RT bloodstream infection.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC the filaments of bacterial flagella. Important for motility and
CC virulence. {ECO:0000256|ARBA:ARBA00025143}.
CC -!- SUBUNIT: Heteromer of FlaA and FlaB. FlaB is located proximal to the
CC hook while the remainder of the filament is composed of the predominant
CC FlaA. {ECO:0000256|ARBA:ARBA00025928}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362073}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362073}.
CC -!- SIMILARITY: Belongs to the bacterial flagellin family.
CC {ECO:0000256|ARBA:ARBA00005709, ECO:0000256|RuleBase:RU362073}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV00738.1}.
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DR EMBL; NESU01000002; PAV00738.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2GUN3; -.
DR Proteomes; UP000218502; Unassembled WGS sequence.
DR GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.2120; -; 1.
DR Gene3D; 1.20.1330.10; f41 fragment of flagellin, N-terminal domain; 1.
DR Gene3D; 6.10.10.10; Flagellar export chaperone, C-terminal domain; 1.
DR InterPro; IPR001492; Flagellin.
DR InterPro; IPR046358; Flagellin_C.
DR InterPro; IPR042187; Flagellin_C_sub2.
DR InterPro; IPR010810; Flagellin_hook_IN_motif.
DR InterPro; IPR001029; Flagellin_N.
DR PANTHER; PTHR42792; FLAGELLIN; 1.
DR PANTHER; PTHR42792:SF2; FLAGELLIN; 1.
DR Pfam; PF00700; Flagellin_C; 1.
DR Pfam; PF07196; Flagellin_IN; 2.
DR Pfam; PF00669; Flagellin_N; 1.
DR PRINTS; PR00207; FLAGELLIN.
DR SUPFAM; SSF64518; Phase 1 flagellin; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362073};
KW Cell projection {ECO:0000313|EMBL:PAV00738.1};
KW Cilium {ECO:0000313|EMBL:PAV00738.1};
KW Flagellum {ECO:0000313|EMBL:PAV00738.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000218502};
KW Secreted {ECO:0000256|RuleBase:RU362073};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT DOMAIN 5..142
FT /note="Flagellin N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00669"
FT DOMAIN 445..530
FT /note="Flagellin C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00700"
SQ SEQUENCE 531 AA; 55352 MW; ADE113BA0EBB5BD5 CRC64;
MAFQVNTNVS ALNAAAQGTF TQYNMKNSLE KLSSGLRINK AADDSSGMTI ADSLRSQASA
LGQAIRNTND GMGIIQIADK AMDEQLKILD TIKVKAVQAG QDGQSTQSRQ AIQADIKRLI
EGLDNIGNTT TYNGLALLSG SFSNKEFQVG AYSNQTIKAS IGAAVSNKIG QVRLETGQNV
TATGEVKLKF VNVDGVNDVE LESVKISSSA GTGLGALVEV INKNSDKTGV RATANVITTS
DEAVKAGSLG GVILNGFSIG DIIGIKDNDS DGRLVQAINA ATMDTGVEAY TDNLGRLNLR
STDGRGIQFS TTGAVAQQGQ NQQAQGNGQT QQQAAGVLAI EKVNGGKDIT AGPDVKNGGN
WNLGRLSLVR TDARDIVISG AGISATGYNT DQTVAEATVN LRDVTGSFDK DIRSASGGNF
NGVFIDESKN LGAGVTSLRG AMVTMDIAES ATKILDKIRA DLGSVQGQMV STVNNITITQ
VNVKAAESQI REVDFAAESS EFSKLNILAQ SGSYALSQAN AVQQNILRLL N
//
