ID A0A2A2HFY8_9GAMM Unreviewed; 521 AA.
AC A0A2A2HFY8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CBG25_04120 {ECO:0000313|EMBL:PAV08371.1};
OS Arsenophonus sp. ENCA.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Arsenophonus.
OX NCBI_TaxID=1987579 {ECO:0000313|EMBL:PAV08371.1, ECO:0000313|Proteomes:UP000217542};
RN [1] {ECO:0000313|EMBL:PAV08371.1, ECO:0000313|Proteomes:UP000217542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ENCA {ECO:0000313|EMBL:PAV08371.1};
RX PubMed=28854637; DOI=10.1093/gbe/evx134;
RA Mao M., Yang X., Poff K., Bennett G.;
RT "Comparative Genomics of the Dual-Obligate Symbionts from the Treehopper,
RT Entylia carinata (Hemiptera: Membracidae), Provide Insight into the Origins
RT and Evolution of an Ancient Symbiosis.";
RL Genome Biol. Evol. 9:1803-1815(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV08371.1}.
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DR EMBL; NHNG01000155; PAV08371.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2HFY8; -.
DR Proteomes; UP000217542; Unassembled WGS sequence.
DR GO; GO:0004657; F:proline dehydrogenase activity; IEA:UniProt.
DR GO; GO:0006562; P:proline catabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.220; -; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR029041; FAD-linked_oxidoreductase-like.
DR InterPro; IPR002872; Proline_DH_dom.
DR PANTHER; PTHR42862; DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR42862:SF1; DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 2, ISOFORM A-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR Pfam; PF01619; Pro_dh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR SUPFAM; SSF51730; FAD-linked oxidoreductase; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000217542}.
FT DOMAIN 17..318
FT /note="Proline dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF01619"
FT DOMAIN 415..511
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 521 AA; 57933 MW; AE08607E7CB12174 CRC64;
MRLMGEQFVT GETITKALSN AHKMENKGFS YSYDMLGEAA LTDEDAKSYM AAYQQAIDAI
GKASHGKSIY ASTGISIKLS ALHARYCRAQ YERVMSELYP RLLTLTLQAR HYDIGINIDA
EEADRLEISL DLLEKLCFEP LLAGWDGIGF VIQAYQKRCP YVIDEIIDLA QRSQHRLMIR
LVKGAYWDSE IKRAQIDGLE GYPVYSRKIY TDVSYLACAR KLLSVPNLIY PQFATHNAHT
LATIYYMAGE NYYPGQYEFQ CLHGMGEGLY QQVVGAIAEG KLNRPCRIYA PVGSHQTLLA
YLVRRLLENG ANTSFVNQIA DPNILLDKLV ADPVQQVLAA AETAGQLGLP HPQIPLPRAL
YGSKRLNAIG IDLTNEHHLA ALAQTLLTTP LCYQVKPLLA GEPPSPAEIS ARQLITNPAN
FDDIVGYVHQ ASLTDVEHAF KIATAAATRW ATTPIIERAA ILQQAACLME QQFSRLIGVL
IREAGKTFSN AIAEVREAID FLRYYAAQIS ENFNNARVSH Q
//
