ID   A0A2A2I9I6_9BACI        Unreviewed;       391 AA.
AC   A0A2A2I9I6;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=MFS transporter {ECO:0000313|EMBL:PAV27805.1};
GN   ORFNames=CIL05_19830 {ECO:0000313|EMBL:PAV27805.1};
OS   Virgibacillus profundi.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Virgibacillus.
OX   NCBI_TaxID=2024555 {ECO:0000313|EMBL:PAV27805.1, ECO:0000313|Proteomes:UP000218887};
RN   [1] {ECO:0000313|EMBL:PAV27805.1, ECO:0000313|Proteomes:UP000218887}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IO3-P3-H5 {ECO:0000313|EMBL:PAV27805.1,
RC   ECO:0000313|Proteomes:UP000218887};
RA   Xu B., Hu B., Wang J., Zhu Y., Huang L., Du W., Huang Y.;
RT   "Virgibacillus indicus sp. nov. and Virgibacillus profoundi sp. nov, two
RT   moderately halophilic bacteria isolated from marine sediment by using the
RT   Microfluidic Streak Plate.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV27805.1}.
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DR   EMBL; NPOA01000018; PAV27805.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2I9I6; -.
DR   OrthoDB; 1650886at2; -.
DR   Proteomes; UP000218887; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR   InterPro; IPR026032; HcaT-like.
DR   InterPro; IPR024989; MFS_assoc_dom.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR23522:SF10; 3-PHENYLPROPIONIC ACID TRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR23522; BLL5896 PROTEIN; 1.
DR   Pfam; PF12832; MFS_1_like; 1.
DR   PIRSF; PIRSF004925; HcaT; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        42..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        95..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        126..149
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        161..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        200..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        265..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        288..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        327..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        355..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          161..391
FT                   /note="Major facilitator superfamily (MFS) profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
SQ   SEQUENCE   391 AA;  42874 MW;  AAF9FEA9DEBB1792 CRC64;
     MSKSNSLTPL KMLLFSFHAT NTIILSYLPL YLKYKGLNGT EIGWVLAVGP LASIVAQPFW
     GYMSDKYKTV KRILQICIVG LLITSVLFFQ MDALIAILLM GAVFYFFVTP IGALGDSLAQ
     RRADDLGISF GTIRMWGSVG FATSSLVIGE ILTRVGIQYM IIPYLFFGTI ALIVTFRLTD
     VKVDSEPVQL KDVTTIIKSK PFVIFLLFIM LLSITHRAND SFMGLYIAQL GGSEGLVGLA
     WFVGVLTEAA VFATAGFWFK KYHPLIFIII AGVLYSIRWL LYSTIDNPMY IVALQFTHGL
     SFGLFYLASF SYVSRLIPKL LQSTGHLIFF ATFFGISGII GSLAGGALID TSGGGTLYFG
     MGILALVGTI LLTVYHVLPY GKESTSSQKA E
//