ID   A0A2A2IF94_9BACI        Unreviewed;       429 AA.
AC   A0A2A2IF94;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Guanine permease {ECO:0000313|EMBL:PAV29805.1};
GN   ORFNames=CIL05_10600 {ECO:0000313|EMBL:PAV29805.1};
OS   Virgibacillus profundi.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Virgibacillus.
OX   NCBI_TaxID=2024555 {ECO:0000313|EMBL:PAV29805.1, ECO:0000313|Proteomes:UP000218887};
RN   [1] {ECO:0000313|EMBL:PAV29805.1, ECO:0000313|Proteomes:UP000218887}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IO3-P3-H5 {ECO:0000313|EMBL:PAV29805.1,
RC   ECO:0000313|Proteomes:UP000218887};
RA   Xu B., Hu B., Wang J., Zhu Y., Huang L., Du W., Huang Y.;
RT   "Virgibacillus indicus sp. nov. and Virgibacillus profoundi sp. nov, two
RT   moderately halophilic bacteria isolated from marine sediment by using the
RT   Microfluidic Streak Plate.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC       Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC       ECO:0000256|PIRNR:PIRNR005353}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV29805.1}.
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DR   EMBL; NPOA01000006; PAV29805.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2IF94; -.
DR   OrthoDB; 9808458at2; -.
DR   Proteomes; UP000218887; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR026033; Azg-like_bact_archaea.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PIRSF; PIRSF005353; PbuG; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT   TRANSMEM        20..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        50..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        93..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        121..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        165..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        193..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        235..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        277..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        338..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        369..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        410..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   429 AA;  45497 MW;  E0C77598BAAD872B CRC64;
     MNKSFRLKQN NTNIRTEVMA GMTTFLTMVY IVVVNPAILS SAGVPFEQVF MATVISAVVG
     TLYMALLANY PIAIAPGMGL NAYFASVVAT QGLSYQVVFG AVFLAGIIFI LLSLTKLRET
     LIVAIPASLK YGITSGIGLF IAFVGLRNSG IVVPNEATIV GLGDLHHPMT LLTIAGLFIT
     LILFVLKVKG ALFFGMLATG IIAFFTGQLD FNGFISAPPS PVFFDMDIGG VISNGLYTVV
     FAFLLVTIFD TTGTMIGVAE QAGFMKNGNM PRAKQALLAD ATATTVGSMF GTSPSTAYIE
     STSGVAAGGR TGLTSVIVAG LFALSIFFTP IIEVIANIPA ITAPILIIVG CFMMEGLAKI
     DWQTFDEAFP AFAIILTMPF TSSIATGIAI GFITYPILKI AVGKGKNVHW ILYVFAVIFL
     LQMIYFPAH
//