ID   A0A2A2J3H7_9BILA        Unreviewed;      1075 AA.
AC   A0A2A2J3H7;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=DM2 domain-containing protein {ECO:0000259|PROSITE:PS51925};
DE   Flags: Fragment;
GN   ORFNames=WR25_15476 {ECO:0000313|EMBL:PAV56360.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV56360.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV56360.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV56360.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- SIMILARITY: Belongs to the tubulin--tyrosine ligase family.
CC       {ECO:0000256|ARBA:ARBA00006820}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV56360.1}.
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DR   EMBL; LIAE01010705; PAV56360.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2J3H7; -.
DR   STRING; 2018661.A0A2A2J3H7; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   GO; GO:0019098; P:reproductive behavior; IEA:UniProt.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   Gene3D; 1.10.245.10; SWIB/MDM2 domain; 1.
DR   InterPro; IPR019835; SWIB_domain.
DR   InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR   InterPro; IPR003121; SWIB_MDM2_domain.
DR   InterPro; IPR004344; TTL/TTLL_fam.
DR   PANTHER; PTHR12241:SF162; TUBULIN MONOGLUTAMYLASE TTLL4; 1.
DR   PANTHER; PTHR12241; TUBULIN POLYGLUTAMYLASE; 1.
DR   Pfam; PF02201; SWIB; 1.
DR   Pfam; PF03133; TTL; 1.
DR   SMART; SM00151; SWIB; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   SUPFAM; SSF47592; SWIB/MDM2 domain; 1.
DR   PROSITE; PS51925; SWIB_MDM2; 1.
DR   PROSITE; PS51221; TTL; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT   DOMAIN          254..331
FT                   /note="DM2"
FT                   /evidence="ECO:0000259|PROSITE:PS51925"
FT   REGION          22..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          492..523
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        495..521
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1075
FT                   /evidence="ECO:0000313|EMBL:PAV56360.1"
SQ   SEQUENCE   1075 AA;  122984 MW;  11D5D1DCF50BC189 CRC64;
     MQHQPRGSAA PAVSLTPMAN RYQQQQPQGM PQSSQPHAVR RPMPGQMIPN LAMQQPGRMQ
     ANKKKRRYID KLIAPKVREL VPESQAYMDL LAYEQKLDAT ISRKKLDIQE TLKRPQKIKR
     RLRIYISHTF LPGREPEREG DEGTTPMWEL RVEGRLLDDI PQNGNGAGNA NGGSGSAVTA
     AAAAAAAASR PISKKKFSSF FKSLVIELDK DIYGPDNHLV EWHRTPTTNE TDGFQVKRPG
     DRPVKCTILL LLDYQPMKFK LHPRLAKVLG VAAETRPKII EALWQYIKTH KLQDPNDRDT
     IMCDVFLEQC FGVKKIRFME VPQRLHQLLS QPDPLVLNHV IQHNEGGAEK NTACYDIDVE
     VEDPMKQHMA SFIHSQQNQQ EIASLDQKIF DIVEQINEWK IRRDFYIRFA DNPHQFIDNW
     VMSQSQDLQV MAEFQGETEA ERRVEAYFAP DIEEGVFRFH GNLHHSLDRR GTAIFLLELI
     CGQSRALVEV ADTDSGRPSS ASSTVNNSEV GSSTPDTPTD NEGMCGLTEL VSSCLAKTRS
     APSGPSSRLC SINDGLPSAS SSQNSKDPQP FLHVSLFTGV PPTIKFYTKG TKVTKPNKKI
     SSRLTWCYNS LLPIVMRHSL AVSHFTVVDE SLFYVGYWGR HLKSAQYKSL HPYQKVNHYP
     GAFHIGRKDR LWMHIKRQID RFGEEEYNII PTTYILPDER EELLEYIRAD PKNHVIMKPP
     ASARGTGISV TRKMKEIPTK GQLQQTKTQM IAQHYVSRPL TINSAKFDLR FYIYVPSLEP
     LRIYIYEEGL VRFASVPYSK NLSTVSNKYM HLTNYSINKL AEKDGVSESP VPKWTLSYLA
     KYFENEGIDW PSIRDRIEDT IVKAFIACEK PIRDHMIKHI RHGFICHELF GVDILLDEDL
     KPWLLEVNIS PSLHSGTPLD VSVKAPLAKD VLNMAGIYVP PSSEMLDEAD YSTRPRNWPK
     TADQILKERL WIDAYLESQE LDPKILKRLT PEDARMLVEF EDERLRCGDF RLLFPIARSA
     HYLRYFEEPV YANLLLQEWQ IEMEADRNAG IDRLEKLCQQ GHMKRRDGKF IGGFW
//