ID A0A2A2J4Q1_9BILA Unreviewed; 1169 AA.
AC A0A2A2J4Q1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PAV56770.1};
GN ORFNames=WR25_05026 {ECO:0000313|EMBL:PAV56770.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV56770.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV56770.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV56770.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV56770.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LIAE01010679; PAV56770.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2J4Q1; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00030; C2; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR46150; RHO GTPASE-ACTIVATING PROTEIN 100F; 1.
DR PANTHER; PTHR46150:SF3; RHO GTPASE-ACTIVATING PROTEIN 100F; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT DOMAIN 423..543
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 580..768
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 74..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1169 AA; 132267 MW; 8304513DD5EBAA2B CRC64;
MSIDDVVLIL SIPRRLLLRI RFSKNFRNQI SSARSAASER PVVVFHRVEE RKDSDQSNTS
ILSNQINTAH TWLGKKARQQ QQEMNRVTQS HHHSENPQPS SSRTYDSPRL VNGHSDIPYY
GRETPPTISN IPNIHHRNPG GSYSARFSDN DTIDTVSRTA RIPPPKIGSA SSASAVRRTE
SFSSAPGVLG HSALYTLPRS STAVPPTSAR DSRDVISNRY DILTHHNPIP TSSASGVDPL
LSRSLCSPIL PRPLRTTMDN KSNSLPRRRA ISGPRNVKWR NDVLQSDVLG EDSDGAVSAP
EYASPSYSRL SPFHPGGRTI NDIFSAAEYR NWAGPMDPRY SQMMSMGMGP WPRQSRWSHT
YGEQPRGPRS TSVPGRSILA QSLANSPVLS RHPMATSLQQ DRPSAVLDRY HVSPLMNRRA
PLRAAGPGIN VDRLTVNSLT GILFVQILEG RGLKIPDKQK GVTEEMYCVL EVDEMHRART
GVSTAEHRYR WRETFHIDVY NATVTHFFVY SWHPQFRHKL CYKGSLKLLE AFIVDQLNGD
RMFALNLEPR GQLIVRIGFQ DMQTVFRRAV NPRMDGVFGV PLSRLLQRER RDTPIVLTRL
IQEIEKRGVD YNGLYILCGS VEKKRMLRDE LETNPLGTEL GVDSVPDTNV LACLVKDFLR
ELPEPLIPVQ IHAMLVDAQM VALPNDASGN RQLVLRIIDC LPAANKNCLI LILDHLTTVL
SAPPNNGLTS NRLNTIFAPL LMCCLDSQLS YSISQNLPTM AKKAPFYATR QIGENLNGIR
FAEYKTPQND PHPEIDTHKI VDPIIVPMMD VFEAMQNNAR VKAYAQKLQE EEQKYPLSSA
KSLWEMLERL QRPSTTTTPQ PPLLERLLQP YIEPWQKQLD DFSKNMAGIT LMPQSSTTPQ
PTTTTTVNLF ERSLGDITVY SNSHSTSYIS FLGKTDFGSI KPIHSKSFDE AIYYRAWCVE
CPDRELILAN VQYEHVLEML ECIHPTYKAV DDQSVHVLLP LAFDYQMEGL LHRCEAFLVN
HNLPFLEKVW LADRYKLNRL LILCLREMRP HSKIDLNGSR YYALSDRVKV LLLERLHGAA
APEEIVEPPL DLEAFQRPSD LFFTGTRAKT GRLYYVNPYY VAAWSNVFQE KIHTLSNTEE
VFCPCTHEEL KAFLMAIHPP QLRINGTCS
//
