ID   A0A2A2J568_9BILA        Unreviewed;       459 AA.
AC   A0A2A2J568;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   22-FEB-2023, entry version 12.
DE   RecName: Full=FH2 domain-containing protein {ECO:0000259|PROSITE:PS51444};
GN   ORFNames=WR25_04066 {ECO:0000313|EMBL:PAV56948.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV56948.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV56948.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV56948.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- SIMILARITY: Belongs to the formin homology family.
CC       {ECO:0000256|ARBA:ARBA00023449}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV56948.1}.
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DR   EMBL; LIAE01010665; PAV56948.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2J568; -.
DR   STRING; 2018661.A0A2A2J568; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR043592; FMNL_animal.
DR   PANTHER; PTHR45857:SF8; FORMIN-HOMOLOGY AND ZINC FINGER DOMAINS PROTEIN 1; 1.
DR   PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR   Pfam; PF02181; FH2; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51444; FH2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT   DOMAIN          54..448
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          46..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          424..459
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        46..68
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   459 AA;  50635 MW;  00DADB3FC086154C CRC64;
     MSTQPNSGGS GNRTEEATTA AAHTEMNEAK PATMDEILNR LANNVNPPTR THSISSSVRS
     SVTQPVRPGE NMQPRYLHTQ ICWSVLNEEQ ARATVFAELS TIENATEMFD GSLLTSPESP
     FILLSEDEAA KVASVRDKLK LQLFEVMFAV HSIARMDLTV LGPELVQLVA EIAPTSADEV
     RMRQFERVAN DAPPLGENEQ FLLALSKIDR LEEKLFVMQH MANFKQKTES IQESLNVLTE
     AAKSINSSAS LKQLLQWILV LMNYFIGDKT GKSIRGFRTS QINEICSRTL HNGETILSLL
     ATTINSDLHE LKGAIDLLPA VNNASQEMFM ELSTAVCRLE EGNILAEREL EFASANNAPL
     TALAEFLEGA RTQITQIFES LISSREELAS MLLFFGEPVP RTEEPFHPEQ FFFNLSSFLT
     SLQAALQPSE SQSQSGKSDS DSTQDSPDSN AEPIHVTSP
//