ID   A0A2A2J6G7_9BILA        Unreviewed;       152 AA.
AC   A0A2A2J6G7;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   03-MAY-2023, entry version 11.
DE   RecName: Full=Mitochondrial fission 1 protein {ECO:0000256|PIRNR:PIRNR008835};
GN   ORFNames=WR25_11466 {ECO:0000313|EMBL:PAV57225.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV57225.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV57225.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV57225.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- FUNCTION: Involved in the fragmentation of the mitochondrial network
CC       and its perinuclear clustering. {ECO:0000256|PIRNR:PIRNR008835}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC       {ECO:0000256|PIRNR:PIRNR008835}.
CC   -!- DOMAIN: The C-terminus is required for mitochondrial localization,
CC       while the N-terminus is necessary for mitochondrial fission.
CC       {ECO:0000256|PIRNR:PIRNR008835}.
CC   -!- SIMILARITY: Belongs to the FIS1 family.
CC       {ECO:0000256|PIRNR:PIRNR008835}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV57225.1}.
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DR   EMBL; LIAE01010651; PAV57225.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2J6G7; -.
DR   STRING; 2018661.A0A2A2J6G7; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000266; P:mitochondrial fission; IEA:UniProtKB-UniRule.
DR   CDD; cd12212; Fis1; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR016543; Fis1.
DR   InterPro; IPR033745; Fis1_cytosol.
DR   InterPro; IPR028061; Fis1_TPR_C.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR13247:SF0; MITOCHONDRIAL FISSION 1 PROTEIN; 1.
DR   PANTHER; PTHR13247; TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11; 1.
DR   Pfam; PF14853; Fis1_TPR_C; 1.
DR   PIRSF; PIRSF008835; TPR_repeat_11_Fis1; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|PIRNR:PIRNR008835, ECO:0000256|SAM:Phobius};
KW   Mitochondrion {ECO:0000256|PIRNR:PIRNR008835};
KW   Mitochondrion outer membrane {ECO:0000256|PIRNR:PIRNR008835};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        127..149
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   152 AA;  17014 MW;  8586D6BFEAE96322 CRC64;
     MISDIDTILD ERVDPFDLEK SRYDYEKQVG RGSPSSLTTF IYANALIRST KEDVHEGINL
     LEKLLHDEPD NGAKRDYVYH LAIANARLKD YDRALAYIDA LLTHEQSNRQ AQRLKEVIEK
     KMRKEGLIGA AIVGTGALVL GGLAALLFAG RK
//