ID A0A2A2J7G9_9BILA Unreviewed; 386 AA.
AC A0A2A2J7G9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=60S ribosome subunit biogenesis protein NIP7 homolog {ECO:0000256|ARBA:ARBA00018162};
GN ORFNames=WR25_02309 {ECO:0000313|EMBL:PAV57559.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV57559.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV57559.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV57559.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- FUNCTION: Required for proper 34S pre-rRNA processing and 60S ribosome
CC subunit assembly. {ECO:0000256|ARBA:ARBA00004087}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nematode receptor-like protein srd family.
CC {ECO:0000256|ARBA:ARBA00009166}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV57559.1}.
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DR EMBL; LIAE01010633; PAV57559.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2J7G9; -.
DR STRING; 2018661.A0A2A2J7G9; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd21146; Nip7_N_euk; 1.
DR CDD; cd21151; PUA_Nip7-like; 1.
DR Gene3D; 3.10.450.220; -; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR InterPro; IPR019421; 7TM_GPCR_serpentine_rcpt_Srd.
DR InterPro; IPR040598; NIP7_N.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR005155; UPF0113_PUA.
DR PANTHER; PTHR22945:SF40; SERPENTINE RECEPTOR, CLASS D (DELTA); 1.
DR PANTHER; PTHR22945; SERPENTINE RECEPTOR, CLASS D DELTA; 1.
DR Pfam; PF10317; 7TM_GPCR_Srd; 1.
DR Pfam; PF03657; UPF0113; 1.
DR Pfam; PF17833; UPF0113_N; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF88802; Pre-PUA domain; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 179..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 95..170
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 386 AA; 43142 MW; 9B5EF1644D52D2EE CRC64;
MRPLTEEETE KVLGKLTYFI GDNVAQLIDR SDGNYCFRNH KERVYYSSEK LMRQASVIAR
EPLLAFGTCL GKFTKTKKFH LHITALDYLA PYAKNRVWLK SQAEQQFLYG NNILKSGIGR
MSEAAPANAG VVVFSMTDTP LGFGVSAKST QDCKKADPTA VVLLHQCDLG EYIRSEATLT
LLLMNSAITE ALACLLAIIV MMRSNITKKE ITLSTGSDDP ALLRYLLLSH FPEYYVDAGT
ISGHLNVVRN FAVAAPIGFV AIVVPSTKKI LNIVAGARYS PHLSRMHTEL LKALTMSAMI
PLLYISSVST YFLLTFQVVR HPFYEDFVFA NANLIPAFSP LVSIFFISPY NRRAHQIWQK
LRCRKMNSFV VSTSVALSQS NEDNRV
//
