ID   A0A2A2J882_9BILA        Unreviewed;      1189 AA.
AC   A0A2A2J882;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=DUF4460 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=WR25_10404 {ECO:0000313|EMBL:PAV57990.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV57990.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV57990.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV57990.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV57990.1}.
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DR   EMBL; LIAE01010608; PAV57990.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2J882; -.
DR   STRING; 2018661.A0A2A2J882; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   InterPro; IPR028031; DUF4460.
DR   InterPro; IPR027989; DUF4461.
DR   InterPro; IPR027986; TCAIM.
DR   PANTHER; PTHR31596; T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR31596:SF1; T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL; 1.
DR   Pfam; PF14687; DUF4460; 1.
DR   Pfam; PF14688; DUF4461; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT   DOMAIN          777..836
FT                   /note="DUF4460"
FT                   /evidence="ECO:0000259|Pfam:PF14687"
FT   DOMAIN          887..1188
FT                   /note="DUF4461"
FT                   /evidence="ECO:0000259|Pfam:PF14688"
FT   REGION          214..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          294..425
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          545..564
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          609..683
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          714..734
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1095..1122
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        223..243
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        244..269
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        294..312
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        329..353
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..381
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        394..425
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1189 AA;  126599 MW;  CD8E7DB335FFC9B6 CRC64;
     MLCDSQEEIS HLMQMIQEVD NYDRTARAEM VVEKFEEYKT KIAITRKMLA DLKAVKKKSI
     QKSSTAEVRD ANEEKYLMKA AQNVNRGIAE SRKKIFKAEE NITLLKRRER VKCLLASVPG
     ESSAAPVELH SLPATAETRL SEKKVHDIVA AQNQIRAFII SMSAQPKRIL PLKVQQFEST
     APPKALNKTL DTSILETSIA QMLVSPRRHV PMSDASTQAN VPLPKPRPVP VVSEPPVPTP
     TAPSQVTSIP STATVQSSNV RPSPTFSTPS ITAAVATSTV TTSAPLFSFK NQPATTTTVA
     SGSPSSIFTT PKIEDKAAQG SDGSKEKTSV FGTPKEPEKA AEVKPEVRSE KADENNGAAP
     PSVSATTPPA ETKSSFSFLT PEKNKPAEPK EASVPVTSAS TSSAFAPSQV SPTPAPTTTS
     SDGFGSLFKT AVTTAAPSTS SSLFGGSTVT SPSTAMTTVS SIFGGTTKPV TTVASSGFSS
     IFGGDASKTG SAAAASQFSF TNAGTAQPTE GTAPKPSSIF GGSSAFGGSA ASNASAAPAS
     SVSFSFKTGS DSAPKPEQKS VFGGSFQTAA SSATAEEGMM DDDLQACNAN TNGQKQSSGL
     FGGAFMSGMG SSSPSSNANR NVFGGSVSNA SNSPGSNSWL FKSNTQNQPT SPSSGGAFSS
     FGAAAKSASP PQQSASPFGA MSSASPSSAF GGAPVFGAKP AFGQKPTFGA GSSFGGMGAL
     SQPQQPAAAP SGGSGFAAFA SNSSSFTAGA SGQSSLFGDR PFRQLMRKLS SLFSISTRHL
     SLNEVSVALR PFYFAVHPDR FARNPEVRDE NEKSLQTGVF RQALESCDAS TANLSEKMSS
     ESVYAENGSE TTQHTVDLQH DLLRNYLRMK KKGMKSNELL HVIKNHNARS DAINKTRNAE
     MARATMKDEI DDIKQRAQLK DIVWGMDWAE SHMRRCLMNV HRLIDYTDAS DRNVVLDCLY
     KNTLRFGRGS FTCCDGSIQL GADHVLEQWR KACMESVIRR KQLPELKESV NQLKTLTDAS
     TILMPYQKGL AQALSQIQTL LVRLHSKSHL LPQLRKYGKD GMFEVVTSYD ELAVGLDGRI
     YIPCNVDVSS LISFLADNKT KAENLQREFT RLTVEVDHAR MQVVQELKLN SLELETGLPL
     KDVLRSMERL LRLSEEDRSS LVGLSLILSI NPFVHVTSSG KLSLPLDWV
//