ID A0A2A2J948_9BILA Unreviewed; 907 AA.
AC A0A2A2J948;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=ABC transmembrane type-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=WR25_11795 {ECO:0000313|EMBL:PAV58193.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV58193.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV58193.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV58193.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV58193.1}.
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DR EMBL; LIAE01010598; PAV58193.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2J948; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18595; ABC_6TM_MRP1_2_3_6_D1_like; 1.
DR CDD; cd03250; ABCC_MRP_domain1; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR PANTHER; PTHR24223:SF443; MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 77..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 738..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 782..805
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 856..875
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 881..904
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 43..326
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 359..585
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 738..907
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT REGION 631..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..650
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 907 AA; 101044 MW; 5DA698907F2C6D3A CRC64;
MSVFPQIFLP EHQKLKECRP ELAAKNLPSI LGPIGKTFKL SLLGAFFLKL CFDLMQFVSP
MLLKLLIKFM EDRSKPIGYG IAIATTMLIS AYLQSMVLHQ YFHIMFRMGM NIRSVLTGAV
YRKALNLSND ARKNRSIGTI VNIMAVDIQR IQDVTSFIML LWSSPQQIII AVFFLYRELG
AAVFAGLAVL VIMLIVNYFI STFVKNIQDE QMKLKDQRIK IMQEILNGIK VVKLYAWEKK
MMNMVDDIRK KELITLRKLA YLNAATTLSW AIAPFLVAVL TFGIYVLIDP ENNVLTPQVT
FVSLALFNIL RFPLAALGIV IPQVVNTKVS VNRLNEFFAE EEIKPEELGR LESSKADAVR
LKEATFAWGA KELNPTLNDV DFTAKRGQLV AIVGRVGSGK SSLLQAILGE MNRISGERLV
SGSAAYVPQQ AWIRNQTLRQ NILFNKPMER DFYELVIDAC ALPPDIAHLP GGDQTEIGEK
GINLSGGQKQ RISLARAVYA NTDIILLDDP LSAVDAHVGK HIFENVISSK TGMLKDKTRI
FVTHGLAFLK HCDQIIVMKD GKICESGGYN ELLSQQGAFS DLIEEFLIEE AKGRGRSVSF
GEDAKDVTEI LDHIDKVNPN KRKALESQIS QEITNQRRSS NVSPTPASPK GESIPMTDVK
KAATAAVAIN GAVAEGNSEP QNAVPLKNEE KQALLESGPA KPAPNKSKII EKEAVQTGKV
DWAVYLAYFK AIGMPITLAF VLIYIASSIA GVFGNLYLAW WSDDAKRIVD EDPSGHETYV
KLGTYSALGM AQATTICLAS IVMTLGMVRA SKYLHTGILK NVLHSPMQFF DVTPLGRIIN
RFSKDVSDID SRLPSFIINF FGSFLQSLMI MFIPIYVTPP ILFFIVPTLV LYYYLCVWIF
GHFLRTW
//
