ID   A0A2A2JC03_9BILA        Unreviewed;       559 AA.
AC   A0A2A2JC03;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Bicarbonate transporter-like transmembrane domain-containing protein {ECO:0000259|Pfam:PF00955};
GN   ORFNames=WR25_15650 {ECO:0000313|EMBL:PAV59308.1};
OS   Diploscapter pachys.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX   NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV59308.1, ECO:0000313|Proteomes:UP000218231};
RN   [1] {ECO:0000313|EMBL:PAV59308.1, ECO:0000313|Proteomes:UP000218231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PF1309 {ECO:0000313|EMBL:PAV59308.1};
RA   Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA   Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT   "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL   Curr. Biol. 0:0-0(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC       {ECO:0000256|ARBA:ARBA00010993}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAV59308.1}.
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DR   EMBL; LIAE01010531; PAV59308.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A2JC03; -.
DR   STRING; 2018661.A0A2A2JC03; -.
DR   Proteomes; UP000218231; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR   GO; GO:0006820; P:monoatomic anion transport; IEA:InterPro.
DR   InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR   InterPro; IPR003020; HCO3_transpt_euk.
DR   InterPro; IPR016152; PTrfase/Anion_transptr.
DR   PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR   PANTHER; PTHR11453:SF121; ANION TRANSPORTER ABTS-2; 1.
DR   Pfam; PF00955; HCO3_cotransp; 2.
DR   SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        228..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        313..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        470..489
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        526..546
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          226..342
FT                   /note="Bicarbonate transporter-like transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF00955"
FT   DOMAIN          414..557
FT                   /note="Bicarbonate transporter-like transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF00955"
SQ   SEQUENCE   559 AA;  63086 MW;  4A12D40FC3C9F6F6 CRC64;
     MNLNTGTLLI CAEEACRARN LSEEIRAKLD AKSLIGSAVI LHNLIDTNMI HIIDKLLDGI
     EKENAKIDKD SVKKELFSIN NDENMGIRFR KKVQQYCKTD FYDINQCWIV LFAEIDNIKK
     RHIALATLKE ATNMGDEAQE MQIIALVIAP KIDKETKSAK ETAQTIATLL TRDELRLGIE
     ECQTSDEIRN LLKQEAEWHL SKKETRIEIG PDGDDSKGVK DSRTISKVIS TAVFLIFTIL
     PTSISYGILN DDNTHGSINV QKVILGQAIG GVVFGLFGGQ QLLILSTTAP LSIYISVIYA
     VCKANDWDFF EMYAAVGIYA QLFLILFALF QMANLMKYTM SVYHELRCLR YYEHYKCVSK
     NGGRLCTIFG IIIRISSLWN RMAIASVRLI KILSVSSSVF KYSCENFPIY STPDVHWIPF
     YNLPGAAHGP AVGLAFPLSL LFFMDQLLVT NTIDNKQHNL AKGSSHHWDL LVVAILNIFL
     SIVGLPWMHG ALPSAFLHLK ALSDVEERLH NGRVQQVIVR VRETRLAVLL AHVLMFPIYF
     YLIPYLNQFI PIALFHGKI
//