ID A0A2A2JD26_9BILA Unreviewed; 1216 AA.
AC A0A2A2JD26;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=ABC transmembrane type-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=WR25_16305 {ECO:0000313|EMBL:PAV59499.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV59499.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV59499.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV59499.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV59499.1}.
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DR EMBL; LIAE01010517; PAV59499.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2JD26; -.
DR STRING; 2018661.A0A2A2JD26; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18595; ABC_6TM_MRP1_2_3_6_D1_like; 1.
DR CDD; cd18603; ABC_6TM_MRP1_2_3_6_D2_like; 1.
DR CDD; cd03250; ABCC_MRP_domain1; 1.
DR CDD; cd03244; ABCC_MRP_domain2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR PANTHER; PTHR24223:SF333; PROTEIN CBR-MRP-8; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000218231};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 239..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..732
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 763..786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 847..875
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 112..394
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 424..649
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 720..1004
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 652..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1216 AA; 136742 MW; B32D5AF4FE982E7B CRC64;
MAEVALLSTS KGADDPAQKQ KNVCPEEGSS IFSRAFFCWM NKILRIGANR TLEFDDLFLL
ADRCKAENLT KTWTKEWTKQ RQTQEKRNAA KKQDKPTSVV WPFIRSQKRI IFFSTFVRVL
SDCIHYLNPL LLKQLIEFVS MPNPPFSFGI AIACIMFVSA ETRSLLQNFQ VNCMFKLNVY
YQSTLQNALL NKVLNLSPSA RASRTAGEIL NHAAVDVEIL IQAIPYLQNL WSVPFQFTLA
MIMLWFTLGP AALAGVTIML IFIPLNYFSS RYIKRYQIAQ MKVKDERTKL SNELLNGMKV
VKLYAWEEPF EERINHLRKE EIRLLKKVCI ASRLIDIFNA TGPFLVAMAS FTCFIFLSED
NVLTPSIAFV SLTVFNQLRQ PMRIFAQLIN TFVQAAVSNK RLSEFLSEEE LQPGVIGVAD
PKVVKLEEAS LNWQGAKFDP TLRDLNITVK PGQFIAIVGT VGSGKSSLLS ALIGEMHVLS
GKVSVGGRLG YAPQQSWITN KTIRDNVLFN ENYNEEFYQR VVRACQLNND FQQFPNGDLT
EVGENGITLS GGQKARVGLA RAVYEDGDIY LLDDPLSAVD AHVGQKLYNE VIGPSGILSK
KTRLLVTHQL QYTREAEVIL VMNEGVIAEQ GTYSELKKKQ GLFSKLLEEM NSQRRQSENA
EEEEPASVRK RKSTMTVDEK SRDGDGQGAK LVQKEQVMMG RVKKSVYVMY FKAMRLINAI
GFFGFFLAHY AATMLRSMWL SDWSNDNTLR VEQPSNLTVE TRLAVYGAIG GFEVILLLLT
FIFLTLGTIR ASYGLHAPLI GALLRAPIGF FDVTPIGRII NRLARDLDVI DKMADSLRQL
TQSMLHVLMI LVLVSFSTPI FLLAAPPLII GYYLVMKYFI PTARQVKRME SVNRSPILSL
FGEVIQGVSS IRAFGKTNVV RQQMMHRVDR FIRCRYMTIS GNRWLATRLE LLGNTTVFFA
SLCGTLSAKY FDLSPGMVGL SVSYALTITE VLNMAVRMLS EIETNIVSVE RVKEYHNIPP
EADWVTEPGP RRDWPEDGAI SLHQYEMRYR DGLPLVLKGI DLEIDGGLKI GVIGRTGSGK
SSLTLALLRM IEATNGYIEI DGTRTDQIGL HQLREKIAII PQEPVLFSGT LRFNLDPFNR
HSDEQIWKAL DSCQLKAFVS SQSDKLDFHV SEGGKNMSVG ERQLLCLGRA ILRGGKLLIL
DEATASGSSL HISLRK
//
