ID A0A2A2JD39_9BILA Unreviewed; 927 AA.
AC A0A2A2JD39;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=WR25_21249 {ECO:0000313|EMBL:PAV59656.1};
OS Diploscapter pachys.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Diploscapter.
OX NCBI_TaxID=2018661 {ECO:0000313|EMBL:PAV59656.1, ECO:0000313|Proteomes:UP000218231};
RN [1] {ECO:0000313|EMBL:PAV59656.1, ECO:0000313|Proteomes:UP000218231}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PF1309 {ECO:0000313|EMBL:PAV59656.1};
RA Fradin H., Zegar C., Gutwein M., Lucas J., Kovtun M., Corcoran D.,
RA Baugh L.R., Kiontke K., Gunsalus K., Fitch D.H., Piano F.;
RT "Genome architecture and evolution of a unichromosomal asexual nematode.";
RL Curr. Biol. 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV59656.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LIAE01010510; PAV59656.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A2JD39; -.
DR STRING; 2018661.A0A2A2JD39; -.
DR Proteomes; UP000218231; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01378; MYSc_Myo1; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140:SF729; HEAVY CHAIN, UNCONVENTIONAL MYOSIN; 1.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000218231}.
FT DOMAIN 14..688
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 726..918
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT REGION 565..587
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 107..114
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 927 AA; 106016 MW; C8A6B93C4615029A CRC64;
MAFHWQSHVN VQHVGVDDMV LLSKLSDQAI VDNLKKRLQA NSIFTYIGPV LISVNPFKQM
PYFTEKEMDQ YQGAAQYENP PHIYATADNM YRNMMIDNEN QCVIISGESG AGKTVAAKFI
MNYISRISGG GQRVQHVKDV ILESNPLLEA FGNSATARNW NSSRFGKYVE IIFSRGGEPI
GGKLSNFLLE KSRVVHQKQG DRNFHIFYQL LAGADKNLRS TLGIGELSYY NYLNQSGVYQ
AQNTDDAKEF KATLHAMSVI GISEEQQFDL FRLVSAVLHI GNITFVEDKN FAAVQSNEFL
EFPAFLLGLS ADAIREKLTT RRMEGKWGKQ TEQIDMTLNV EQAVYTRDAW VKAIYSRMFD
FLVKSVNGAM EIPARDSALS IGILDIYGFE IFDHNGFEQF CINFINEKLQ QIFIELTLKA
EQEEYVKEGV QWTPVEYFDN KIVCELIESK RPPGIMSLLD DTCAQNHGQS EGVDRQFLTT
LSKAHAGHPH LQQGAECFLI RHYAGDVTYH IEGFCDTNRD VLYPDLIQLM QQSTNPFVRS
LFPDQVNAGG AKRPTTFSTK IRSQANDLVD SLMKCTPHYV RCIKPNETKR AGDWDERRVL
HQVQYLGLKE NIRVRRAGFA YRRSFEKFLW RYAILTEQTW PSYRGPPQQG CEIICQSVNM
DRGQYQMGKT KIFIKNPESL FLLEEVRERK YDGFARKIQK AWRQFNARKH HAKQKEEACD
LMYGKKERRR FSLNRNFVGD YIGLEYKPAL QALVGKRERV DFAHTANKYD RRFKISKVDL
LVTSKHVTLI GREKVKKGPE KGKLVEVVKR QLELGKIASI GLSPYQDDFL ILQVRDDYSS
LLETPFKTEF CTAVSKRYKE KMNGAILPLE FKNSHVVTLK KTRFGGGTRT VNFVVEESEN
RAAVLKPNGK ILNVAIGRGL SNTTSEQ
//
